LUNG TRANSPLANTATION
Clinical trials for LUNG TRANSPLANTATION explained in plain language.
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New drug switch for young transplant patients shows promise
Disease control CompletedThis study tested switching children who had stable organ transplants from one immunosuppressant (Prograf) to a longer-acting version (Advagraf). The goal was to compare drug levels in the body and monitor safety and effectiveness over one year, with extended follow-up. 81 childr…
Matched conditions: LUNG TRANSPLANTATION
Phase: PHASE2 • Sponsor: Astellas Pharma Europe Ltd. • Aim: Disease control
Last updated Jun 15, 2026 18:57 UTC
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New combo therapy for lung transplant patients shows promise in antibody clearance
Disease control CompletedThis study looked at 340 lung transplant patients who had donor-specific antibodies, which can cause organ rejection. They received a combination of immunoglobulin therapy, plasmapheresis, and rituximab. The goal was to see if the antibodies cleared and if the transplanted lungs …
Matched conditions: LUNG TRANSPLANTATION
Sponsor: Hannover Medical School • Aim: Disease control
Last updated Jun 12, 2026 12:06 UTC
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Face-Down donors could boost lung transplants
Knowledge-focused CompletedThis study tested whether placing brain-dead organ donors on their stomach (prone position) helps keep their lungs healthy enough for transplant. Researchers compared this to the usual back-lying (supine) position in 254 donors across 10 hospitals in Argentina. The goal was to se…
Matched conditions: LUNG TRANSPLANTATION
Phase: NA • Sponsor: Hospital de Alta Complejidad del Bicentenario Esteban Echeverría • Aim: Knowledge-focused
Last updated Jun 17, 2026 12:07 UTC
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New study checks if Baby's genes raise rejection risk in lung transplant moms
Knowledge-focused CompletedThis study looked at women with lung transplants who had babies between 2012 and 2021. Researchers checked if the baby and the lung donor share certain immune markers (HLA types) that might increase the risk of organ rejection. By collecting cheek swabs from the children, they ho…
Matched conditions: LUNG TRANSPLANTATION
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:52 UTC
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New clues to spot lung transplant trouble early
Knowledge-focused CompletedThis study looked at 80 people who had a lung transplant to see if two simple tests could warn doctors early when a patient's health starts to get worse. The tests measured breathing effort (neural respiratory drive) and a heart-related protein (Pro-BNP) in the blood. The goal wa…
Matched conditions: LUNG TRANSPLANTATION
Sponsor: The First Affiliated Hospital of Guangzhou Medical University • Aim: Knowledge-focused
Last updated Jun 11, 2026 12:11 UTC