LOWER EXTREMITY
Clinical trials for LOWER EXTREMITY explained in plain language.
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Placental patch shows promise for stubborn diabetic wounds
Disease control Recruiting nowThis study tests a special wound dressing made from donated placental tissue, called Matrion, to see if it helps diabetic foot ulcers heal faster than standard care. About 120 adults with diabetes and a foot wound below the ankle will take part. The goal is to improve healing and…
Matched conditions: LOWER EXTREMITY
Phase: NA • Sponsor: LifeNet Health • Aim: Disease control
Last updated May 29, 2026 14:19 UTC
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New Light-Based scan could catch hidden leg artery disease
Diagnosis Recruiting nowThis study tests a new imaging technique called photoacoustic tomography (PACT) to better detect lower extremity artery disease (LEAD), a condition where leg arteries become narrowed or blocked. Current methods often miss the disease, leading to serious complications. The study w…
Matched conditions: LOWER EXTREMITY
Sponsor: Sun Yat-sen University • Aim: Diagnosis
Last updated Jun 10, 2026 13:29 UTC
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New drug combo aims to ease pain after leg amputation
Symptom relief Recruiting nowThis study compares two pain relief methods during spinal anesthesia for above-knee amputation due to lower leg sarcoma. One group gets a standard painkiller (fentanyl) plus an extra drug (dexmedetomidine), while the other gets fentanyl alone. The goal is to see if the combinatio…
Matched conditions: LOWER EXTREMITY
Phase: NA • Sponsor: National Cancer Institute, Egypt • Aim: Symptom relief
Last updated Jun 15, 2026 18:54 UTC
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New bandage may cut infections after leg skin grafts
Symptom relief Recruiting nowThis study tests whether a special vacuum bandage (negative pressure wound therapy) can prevent infections better than standard dressings after skin grafts on the lower leg. About 242 adults who have a skin tumor removed and need a skin graft will take part. The bandage is applie…
Matched conditions: LOWER EXTREMITY
Phase: NA • Sponsor: Region Skane • Aim: Symptom relief
Last updated Jun 12, 2026 12:08 UTC
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Which numbing cocktail works faster for leg surgery pain?
Symptom relief Recruiting nowThis study tests if mixing two numbing drugs (lidocaine and bupivacaine) works faster than using just one (bupivacaine) for a nerve block before leg surgery. About 60 adults having elective below-knee surgery will receive one of the two treatments. Researchers will measure how qu…
Matched conditions: LOWER EXTREMITY
Phase: NA • Sponsor: Ataturk University • Aim: Symptom relief
Last updated Jun 12, 2026 12:07 UTC