LOWER BACK PAIN

This early-stage study tests a new drug called CNTX-3001 for people with long-term, moderate to severe low back pain that hasn't gotten better with other treatments. The drug is given as a single injection into the fluid around the spinal cord. The main goal is to check if it's s…

This study tests whether using a dynamic office chair can lower lower back pain and improve overall well-being in office workers. About 20 adults who develop back pain during a workday will try the chair for several weeks. Researchers will measure pain and mental fatigue before a…

This study tests whether dry needling—a technique where thin needles are inserted into muscles—can reduce pain and improve quality of life for people with chronic low back pain. Researchers will also check if the approach is practical and acceptable. The study includes 42 adults,…

This study is testing whether a one-time infusion of stem cells and exosomes from donated umbilical cord blood can safely reduce chronic lower back pain and improve daily function. About 100 adults with long-term back pain will receive either the stem cell treatment or a placebo …

This study looks at whether adding weekly medical massage therapy to standard care helps active-duty service members with subacute lower back pain recover more quickly. About 220 participants will either receive standard care alone or standard care plus massage for 12 weeks. Rese…

This study tests a cushion called DaSuit® in 20 adults with low back pain that gets worse when sitting. Participants sit on the cushion or a fake one for 10 minutes each, while sensors measure pressure under their buttocks and X-rays check spine alignment. The goal is to see if t…

This study tests whether a temporary nerve stimulator called SPRINT can safely reduce chronic lower back pain caused by the sacroiliac joint. Ten adults with severe pain will receive the stimulator under the skin for a short time and be followed for three months. The goal is to s…

This study compares a robotic massage device (EMMA) to a human massage therapist for relieving lower back pain. Researchers want to see if people find the robot acceptable and if it's practical to use. About 40 adults with lower back pain will take part.

This study looks at how many medical students at the University of the West Indies, Mona, have neck or low back pain. It also checks what students know about spine health and tests whether a standard exercise program can reduce their pain. About 1,000 students will take part, and…

This study looks at how inhaled cannabis affects the brain in people with chronic low back pain. Researchers will use MRI scans to measure changes in brain blood flow and oxygen levels, and ask participants to rate their pain. The goal is to understand the brain mechanisms behind…