LOCALLY ADVANCED BREAST CANCER (LABC)
Clinical trials for LOCALLY ADVANCED BREAST CANCER (LABC) explained in plain language.
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New hope for advanced breast cancer: experimental combo targets hard-to-treat tumors
Disease control Not yet recruitingThis study tests a new combination of two drugs (JSKN016 and D-0502) in people with a common type of advanced breast cancer (HR-positive, HER2-negative) that has worsened after standard hormone therapy. About 60 adults will receive the drugs either every 2 or 3 weeks. The goal is…
Matched conditions: LOCALLY ADVANCED BREAST CANCER (LABC)
Phase: PHASE1, PHASE2 • Sponsor: Jiangsu Alphamab Biopharmaceuticals Co., Ltd • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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New drug cocktail aims to shrink Hard-to-Treat breast tumors before surgery
Disease control Not yet recruitingThis early-stage study tests whether adding two targeted drugs (pyrotinib and darcilib) to standard hormone therapy can shrink tumors before surgery in people with HR-positive, HER2-low breast cancer. The trial plans to enroll 33 patients with locally advanced disease. The main g…
Matched conditions: LOCALLY ADVANCED BREAST CANCER (LABC)
Phase: PHASE1, PHASE2 • Sponsor: The First Affiliated Hospital of Xiamen University • Aim: Disease control
Last updated May 06, 2026 16:03 UTC
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Pre-Surgery stretches may ease pain after breast cancer surgery
Symptom relief Not yet recruitingThis study looks at whether doing shoulder range-of-motion exercises for 6-8 weeks before a mastectomy can lower inflammation, pain, and shoulder problems after surgery. About 52 adults with advanced breast cancer will take part. The goal is to see if these simple exercises impro…
Matched conditions: LOCALLY ADVANCED BREAST CANCER (LABC)
Phase: NA • Sponsor: Indonesia University • Aim: Symptom relief
Last updated May 15, 2026 12:07 UTC
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Mind over tumor: brief therapy may boost chemo power
Symptom relief Not yet recruitingThis study looks at whether a short form of talk therapy (Brief Acceptance and Commitment Therapy) can help women with locally advanced breast cancer get better results from chemotherapy before surgery. Researchers will measure tumor shrinkage, stress levels, and blood markers of…
Matched conditions: LOCALLY ADVANCED BREAST CANCER (LABC)
Phase: NA • Sponsor: Universitas Airlangga • Aim: Symptom relief
Last updated May 12, 2026 13:43 UTC
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Lab-Grown tumors could unlock secrets of chemo resistance in breast cancer
Knowledge-focused Not yet recruitingThis study aims to understand why some breast cancers resist chemotherapy. Researchers will grow mini-tumors (organoids) from patient samples and test how they respond to drugs. The goal is to find ways to predict and overcome resistance, but this is an observational study with n…
Matched conditions: LOCALLY ADVANCED BREAST CANCER (LABC)
Sponsor: Atlas University • Aim: Knowledge-focused
Last updated May 17, 2026 01:00 UTC