LOCALLY ADVANCED BREAST CANCER (LABC)
Clinical trials for LOCALLY ADVANCED BREAST CANCER (LABC) explained in plain language.
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New hope for hard-to-treat breast cancer: combo therapy enters human trials
Disease control Not yet recruitingThis study tests a new two-drug combination (JSKN016 plus D-0502) in 60 people with advanced hormone receptor-positive, HER2-negative breast cancer whose disease worsened after standard hormone therapy. The goal is to see if the combination is safe and shrinks tumors. Participant…
Matched conditions: LOCALLY ADVANCED BREAST CANCER (LABC)
Phase: PHASE1, PHASE2 • Sponsor: Jiangsu Alphamab Biopharmaceuticals Co., Ltd • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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New drug cocktail aims to shrink breast tumors before surgery
Disease control Not yet recruitingThis early-phase study is testing whether combining two targeted drugs (pyrotinib and dalpiciclib) with standard hormone therapy can shrink tumors in people with HR+HER2 low breast cancer before they have surgery. The study plans to enroll 33 patients with locally advanced diseas…
Matched conditions: LOCALLY ADVANCED BREAST CANCER (LABC)
Phase: PHASE1, PHASE2 • Sponsor: The First Affiliated Hospital of Xiamen University • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Mind over tumor: short therapy may improve chemo response in breast cancer
Symptom relief Not yet recruitingThis study tests whether a short psychological therapy called Brief Acceptance and Commitment Therapy (Brief-ACT) can help chemotherapy work better in women with locally advanced breast cancer. Fifty-four participants will either receive standard chemotherapy alone or with Brief-…
Matched conditions: LOCALLY ADVANCED BREAST CANCER (LABC)
Phase: NA • Sponsor: Universitas Airlangga • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Simple Pre-Surgery shoulder stretches may ease pain after breast cancer surgery
Symptom relief Not yet recruitingThis study looks at whether doing shoulder exercises before a mastectomy can lower inflammation, reduce pain, and improve shoulder function and quality of life in women with advanced breast cancer. Half of the 52 participants will do structured shoulder exercises for 6-8 weeks be…
Matched conditions: LOCALLY ADVANCED BREAST CANCER (LABC)
Phase: NA • Sponsor: Indonesia University • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Lab-Grown mini tumors could unlock secrets of chemo resistance in breast cancer
Knowledge-focused Not yet recruitingThis study will take tumor samples from 40 women with locally advanced breast cancer and grow them in the lab as 3D 'mini tumors' called organoids. Researchers will test how these organoids respond to chemotherapy and compare the results to how the patients actually responded. Th…
Matched conditions: LOCALLY ADVANCED BREAST CANCER (LABC)
Sponsor: Atlas University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC