LANGERHANS CELL HISTIOCYTOSIS
Clinical trials for LANGERHANS CELL HISTIOCYTOSIS explained in plain language.
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Experimental drug shows promise for rare immune disorder
Disease control OngoingThis study tests the drug clofarabine in 25 people with Langerhans cell histiocytosis (LCH) or related disorders that have returned or not improved with standard therapy. The goal is to see if clofarabine can shrink or eliminate disease. Participants receive the drug and are moni…
Matched conditions: LANGERHANS CELL HISTIOCYTOSIS
Phase: PHASE2 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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New hope for kids with rare immune disorder: international trial tests drug cocktails
Disease control OngoingThis study tests several drug combinations and stem cell transplants in 1,400 children with Langerhans cell histiocytosis, a rare immune disease. The goal is to prevent the disease from coming back and reduce lasting problems like hormone deficiencies and brain issues. Researcher…
Matched conditions: LANGERHANS CELL HISTIOCYTOSIS
Phase: PHASE2, PHASE3 • Sponsor: North American Consortium for Histiocytosis • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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New stem cell approach could fix immune systems in kids
Disease control OngoingThis Phase II trial tests a stem cell transplant from unrelated or partially matched family donors for children and young adults with severe immune deficiencies. The stem cells are specially processed to remove certain immune cells, aiming to reduce complications. The goal is to …
Matched conditions: LANGERHANS CELL HISTIOCYTOSIS
Phase: PHASE2 • Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Can DNA tests pick the right cancer drug for kids?
Knowledge-focused OngoingThis study screens children and teens with advanced solid tumors, lymphomas, or histiocytic disorders to find genetic changes in their cancer cells. Participants undergo biopsies and scans to identify mutations that can be targeted by specific drugs. The goal is to see if matchin…
Matched conditions: LANGERHANS CELL HISTIOCYTOSIS
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Rare disease study probes hidden brain effects
Knowledge-focused OngoingThis study looks at how histiocytosis—a group of rare disorders—may affect memory, thinking, and brain structure. Researchers will test 13 adults with these conditions using thinking tasks and MRI scans. The goal is to better understand brain changes, not to provide treatment.…
Matched conditions: LANGERHANS CELL HISTIOCYTOSIS
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Massive childhood cancer registry launches to unlock secrets of the disease
Knowledge-focused OngoingThis study is a large registry that collects information from children diagnosed with cancer across the US and Canada. Its goal is to help researchers understand patterns, causes, and characteristics of childhood cancer. No treatments or drugs are given—it is purely for research …
Matched conditions: LANGERHANS CELL HISTIOCYTOSIS
Sponsor: Children's Oncology Group • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC