Experimental drug shows promise for rare immune disorder
NCT ID NCT02425904
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests the drug clofarabine in 25 people with Langerhans cell histiocytosis (LCH) or related disorders that have returned or not improved with standard therapy. The goal is to see if clofarabine can shrink or eliminate disease. Participants receive the drug and are monitored for response and side effects.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Arkansas Children's Hospital
Little Rock, Arkansas, 72202, United States
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Boston Children's Hospital
Boston, Massachusetts, 02115, United States
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Children's Hospital of Los Angeles
Los Angeles, California, 90027, United States
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Children's National Medical Center
Washington D.C., District of Columbia, 20010, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02115, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Mount Sinai Medical Center
New York, New York, 10029, United States
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Phoenix Children's Hospital
Phoenix, Arizona, 85016, United States
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St. Jude Children's Research Hospital
Memphis, Tennessee, 38105, United States
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Texas Children's Hospital
Houston, Texas, 77030, United States
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The Children's Hospital of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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The Hospital for Sick Children
Toronto, Ontario, M5G 1X8, Canada
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University of California San Francisco Medical Center
San Francisco, California, 94143, United States
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Other studies related to the condition(s) this trial covers.
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