ISCHEMIA
Clinical trials for ISCHEMIA explained in plain language.
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Stem cell shots before amputation aim to save limbs
Disease control CompletedThis early-phase study tested whether injecting donor stem cells into the leg before amputation could prevent wound complications and reduce the need for further surgery. 81 adults aged 40-90 with severe leg artery disease received the injections. The main goal was to check safet…
Matched conditions: ISCHEMIA
Phase: PHASE1 • Sponsor: Indiana University • Aim: Disease control
Last updated May 13, 2026 16:01 UTC
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Heart plaque study tests aggressive meds in women
Knowledge-focused CompletedThis study looked at 191 women with non-obstructive coronary artery disease (plaque that doesn't fully block arteries). Researchers used CT scans to compare intensive medical therapy versus usual care, measuring changes in plaque amount, type, and inflammation. The goal was to un…
Matched conditions: ISCHEMIA
Sponsor: Cedars-Sinai Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 07:38 UTC
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New pilot trainer targets blackout risks
Knowledge-focused CompletedThis study tested a prototype system that uses a tilt table and lower body pressure chamber to create conditions of low blood pressure and blood pooling in the legs. The goal is to help military pilots train to avoid blackouts and improve safety. 46 pilots and cadets took part, a…
Matched conditions: ISCHEMIA
Phase: NA • Sponsor: Military Institute of Aviation Medicine • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC