INHERITED BONE MARROW FAILURE SYNDROME
Clinical trials for INHERITED BONE MARROW FAILURE SYNDROME explained in plain language.
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Could a cancer drug fix a rare bleeding disorder?
Disease control Recruiting nowThis study tests imatinib, a pill taken daily, in adults with a faulty RUNX1 gene that causes easy bleeding and a higher risk of blood cancers. The goal is to find the best dose and see if it improves platelet function and reduces inflammation. Participants take the drug for 28 t…
Matched conditions: INHERITED BONE MARROW FAILURE SYNDROME
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 17, 2026 02:15 UTC
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New combo aims to stop blood cancer relapse after transplant in kids
Disease control Recruiting nowThis study tests whether giving two drugs (decitabine and filgrastim) after a stem cell transplant can safely prevent leukemia or related blood cancers from coming back in children and young adults. About 37 participants with acute myeloid leukemia, myelodysplastic syndromes, or …
Matched conditions: INHERITED BONE MARROW FAILURE SYNDROME
Phase: PHASE2 • Sponsor: Franziska Wachter • Aim: Disease control
Last updated May 17, 2026 02:14 UTC
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Can a simple genetic test catch blood cancers before they start?
Knowledge-focused Recruiting nowThis study uses advanced genetic testing (next generation sequencing) to look for early warning signs of pre-myeloid cancers and bone marrow failure in 2000 people. Participants have certain blood abnormalities or genetic markers that may increase their risk. The goal is to bette…
Matched conditions: INHERITED BONE MARROW FAILURE SYNDROME
Phase: NA • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 17, 2026 02:15 UTC
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New study aims to catch cancer early in rare genetic disorder
Knowledge-focused Recruiting nowThis study follows people with Fanconi anemia, a rare inherited condition that raises the risk of certain cancers, especially squamous cell carcinoma. Researchers will screen participants yearly for up to 10 years using exams, blood tests, and imaging to find early signs of cance…
Matched conditions: INHERITED BONE MARROW FAILURE SYNDROME
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated May 17, 2026 02:02 UTC