INFECTIONS

This study follows about 338 healthy pregnant women in Denmark and South Africa who previously received the GBS-NN/NN2 vaccine. Researchers want to see if the immune protection lasts and if a booster dose during a new pregnancy is safe and effective. The goal is to help prevent s…

This study looks at the best way to prevent infections in children with mild open fractures (broken bones that poke through the skin). About 800 kids will get either one dose, 24 hours, or 24 hours plus 5 days of antibiotics. The goal is to see if shorter treatment works just as …

This study tests if bevacizumab, a drug that blocks blood vessel growth, can help adults with recurrent respiratory papillomatosis (RRP) go longer between surgeries to remove wart-like growths in their airways. About 21 participants who need at least two surgeries per year will r…

This study looks at 400,000 people who gave birth between 2014 and 2021 to find better ways to predict and prevent maternal sepsis, a leading cause of death in new mothers. The goal is to understand how social factors like race, poverty, and community affect risk, especially for …

This study looks at whether treating patients at home for conditions like infections, heart failure, and diabetes can lead to better health outcomes and satisfaction compared to a hospital stay. About 9,600 adults will receive hospital-level care in their own homes through a digi…

This study aims to understand how the immune system responds to a second infection with a mild bird flu virus (H10N7). Healthy adults who were infected with H10N7 in a previous study will be infected again and monitored closely in the hospital for 9 days. The goal is to learn mor…

This study is watching how infections like COVID-19 spread among people and between people and their pets in the Canton of Bern, Switzerland. Over 2,000 participants are providing samples and answering surveys to help scientists understand social and environmental factors that af…

This study tests a new digital platform that helps doctors and nurses share important patient information when a person is moved from one hospital to another. About 1,000 adults being transferred to a major hospital will take part. The goal is to see if better information sharing…

This study tests whether infant formula with added bio-active ingredients helps healthy babies grow well and have fewer infections compared to standard formula. About 456 full-term, healthy infants will be enrolled and followed for several months. Parents will report any infectio…

This study looks at whether taking daily vitamin D and omega-3 (fish oil) supplements can lower the risk of infections like colds, flu, and urinary tract infections in over 25,000 healthy adults. It also measures a natural germ-fighting protein in the blood. The goal is to learn,…

This study planned to see if an artificial intelligence system could predict sepsis—a dangerous infection—in people recovering from abdominal surgery. Participants would have worn a simple, non-invasive device to track vital signs. However, the study was withdrawn before any volu…

This study looks at how social factors like poverty and race affect care for mothers with sepsis, a leading cause of death after childbirth in the U.S. Researchers will interview 200 Spanish- or English-speaking women who recently gave birth and had infection warning signs, plus …