IGA VASCULITIS

This study tests an experimental drug called sparsentan in 67 children with certain kidney diseases that cause protein leakage in urine. The goal is to see if the drug is safe and can reduce protein levels over 108 weeks. Participants take the drug once daily as a liquid or table…

This study compares three standard treatments for people with isolated skin vasculitis, a condition where blood vessels in the skin become inflamed. The goal is to see which treatment works best to control symptoms and improve quality of life. About 90 adults will take part and b…

This study tests a drug called ravulizumab in children aged 2 to 18 with a kidney disease called IgA nephropathy. The goal is to see if the drug can reduce protein in the urine, a sign of kidney damage. Participants will receive the drug through an IV and be monitored for safety …

This study looks at skin samples from 50 people with different types of vasculitis, a condition where blood vessels become inflamed. Researchers want to understand how the disease affects the skin at a molecular level. Participants must have an active skin rash related to their v…

This study gathers information from women with vasculitis who become pregnant. Participants fill out online surveys about their disease and pregnancy experiences. The goal is to learn more about pregnancy outcomes in this group. No treatments or medications are tested.

This study gathers existing tissue samples from 1,000 people with various forms of vasculitis, a group of rare diseases that cause blood vessel inflammation. Researchers will analyze the tissue alongside medical data to find genes linked to the disease. The goal is to better unde…