IDH2 GENE MUTATION
Clinical trials for IDH2 GENE MUTATION explained in plain language.
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New hope for young brain tumor patients: drug duo targets hard-to-treat gliomas
Disease control OngoingThis early-stage study tests a new drug (BGB-290) combined with chemotherapy (temozolomide) in adolescents and young adults with IDH-mutant gliomas, a type of brain tumor. The goal is to find the safest dose and check for side effects. About 78 participants with newly diagnosed o…
Matched conditions: IDH2 GENE MUTATION
Phase: PHASE1 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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New study probes niraparib's brain tumor penetration in IDH-mutant gliomas
Knowledge-focused OngoingThis early-phase trial enrolls 16 adults with recurrent IDH-mutant gliomas who are scheduled for surgery. Participants take niraparib for one month before their operation. The main goal is to measure how much drug gets into the tumor and how it affects cancer cell activity, not t…
Matched conditions: IDH2 GENE MUTATION
Phase: EARLY_PHASE1 • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated May 17, 2026 08:04 UTC