IDH MUTATION
Clinical trials for IDH MUTATION explained in plain language.
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New combo therapy aims to reignite immune attack on brain tumors
Disease control Recruiting nowThis study tests a combination of two drugs—ATRA and retifanlimab—in people with a recurrent type of brain tumor called IDH-mutant glioma. The goal is to see if this treatment can shrink tumors or slow their growth by boosting the body's immune response. About 55 participants wil…
Matched conditions: IDH MUTATION
Phase: PHASE2 • Sponsor: Stephen Bagley, MD, MSCE • Aim: Disease control
Last updated Apr 30, 2026 15:51 UTC
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New hope for bile duct cancer: targeted pill may prevent recurrence after standard treatment
Disease control Recruiting nowThis study tests whether a daily pill called ivosidenib can help prevent bile duct cancer from returning in people who have already had surgery and chemotherapy. The drug targets a specific genetic change (IDH1 mutation) found in some bile duct cancers. About 40 adults with this …
Matched conditions: IDH MUTATION
Phase: PHASE2 • Sponsor: Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest • Aim: Disease control
Last updated Apr 30, 2026 15:48 UTC
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Patients' voices heard: new study compares brain tumor treatments through their eyes
Knowledge-focused Recruiting nowThis study looks at how patients with a slow-growing brain tumor (IDH-mutant grade 2 glioma) feel during treatment. It compares two groups: those getting radiotherapy and those taking a drug called vorasidenib. A third group just gets regular check-ups. The goal is to understand …
Matched conditions: IDH MUTATION
Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:03 UTC