HYPERPHOSPHATEMIA

This study tested a new drug called AP301 to see if it works as well as or better than a standard medication (sevelamer) at controlling high phosphorus levels in the blood of people on long-term dialysis. It involved 474 Chinese adults with chronic kidney disease who were receivi…

This study tested the long-term safety of MCI-196, a medication that helps control high phosphorus levels in people with advanced kidney disease who are on dialysis. The research followed 632 patients for up to one year to monitor how well they tolerated the medication and whethe…

This large, completed Phase 3 trial tested whether the drug MCI-196 could help control two common problems in people with kidney failure on dialysis: high phosphorus and high 'bad' cholesterol. The study involved 642 stable dialysis patients who were randomly assigned to receive …

This study tested whether the drug MCI-196 could safely control high phosphorus levels in people with kidney failure on dialysis. Researchers compared the drug against a placebo in 336 patients over 16 weeks. The goal was to see if the drug could effectively manage this common an…

This study tested whether a drug called MCI-196 could safely and effectively control high phosphorus levels in the blood of adults with kidney failure who are on dialysis. After a 12-week period where all participants received the drug, some were randomly switched to a placebo (d…

This study tested the long-term safety and effectiveness of a drug called MCI-196 for people on dialysis who have high phosphate levels in their blood. It involved 116 adult patients on stable dialysis treatment. The main goal was to see how safe the drug was over a year, while a…

This study aimed to see if taking a phosphate-lowering drug (colestilan) changes how the body absorbs a common blood pressure medication (candesartan). It involved 18 healthy male volunteers to measure drug levels in the blood under different timing schedules. The goal was to gat…