HYPERCORTISOLISM
Clinical trials for HYPERCORTISOLISM explained in plain language.
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New drug shows promise for cortisol disorder in phase 3 trial
Disease control CompletedThis study tested a drug called relacorilant in 137 people with high cortisol levels due to non-cancerous adrenal gland growths. The goal was to see if the drug could improve blood pressure and blood sugar control. Participants received either the drug or a placebo, and researche…
Matched conditions: HYPERCORTISOLISM
Phase: PHASE3 • Sponsor: Corcept Therapeutics • Aim: Disease control
Last updated May 17, 2026 02:37 UTC
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Cortisol-Blocking drug shows promise for blood pressure and sugar control
Disease control CompletedThis study looked at whether metyrapone, a drug that lowers cortisol, can improve health in 20 adults with mild Cushing's syndrome (a condition of high cortisol). Researchers measured changes in blood pressure, blood sugar, cholesterol, and mood over the treatment period. The goa…
Matched conditions: HYPERCORTISOLISM
Sponsor: Istituto Auxologico Italiano • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Spit test could replace needle for adrenal diagnosis
Diagnosis CompletedThis study looked at whether measuring cortisol in saliva works as well as measuring it in blood after taking a small steroid pill. Researchers compared 100 people with adrenal tumors and 100 healthy volunteers. The goal was to see if the simpler saliva test could accurately dete…
Matched conditions: HYPERCORTISOLISM
Sponsor: Rigshospitalet, Denmark • Aim: Diagnosis
Last updated May 17, 2026 02:34 UTC
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Hidden hormone culprit found in many tough blood pressure cases
Knowledge-focused CompletedThis study looked at over 1,100 adults in the US whose high blood pressure stays high despite taking multiple medications. Researchers checked how many also have a hormone condition called endogenous hypercortisolism (too much cortisol). Participants provided blood and urine samp…
Matched conditions: HYPERCORTISOLISM
Sponsor: Corcept Therapeutics • Aim: Knowledge-focused
Last updated May 17, 2026 02:36 UTC