HORMONE RECEPTOR-POSITIVE/HER2 NEGATIVE BREAST CANCER
Clinical trials for HORMONE RECEPTOR-POSITIVE/HER2 NEGATIVE BREAST CANCER explained in plain language.
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New hope for hard-to-treat breast cancer: drug duo targets hidden mutations
Disease control Not yet recruitingThis study tests a combination of two drugs, zongertinib and fulvestrant, in people with advanced breast cancer that is hormone receptor-positive and HER2-negative but has a specific HER2 gene mutation. The goal is to see if the combination shrinks tumors. About 25 adults will ta…
Matched conditions: HORMONE RECEPTOR-POSITIVE/HER2 NEGATIVE BREAST CANCER
Phase: PHASE2 • Sponsor: MedSIR • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New hope for hard-to-treat breast cancer: combo therapy enters human trials
Disease control Not yet recruitingThis study tests a new two-drug combination (JSKN016 plus D-0502) in 60 people with advanced hormone receptor-positive, HER2-negative breast cancer whose disease worsened after standard hormone therapy. The goal is to see if the combination is safe and shrinks tumors. Participant…
Matched conditions: HORMONE RECEPTOR-POSITIVE/HER2 NEGATIVE BREAST CANCER
Phase: PHASE1, PHASE2 • Sponsor: Jiangsu Alphamab Biopharmaceuticals Co., Ltd • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Could hormone therapy replace chemo for young breast cancer patients?
Disease control Not yet recruitingThis study looks at 4,000 women aged 50 or younger with a common type of early breast cancer. Researchers want to see if hormone therapy plus ovarian function suppression works as well as chemotherapy for those with certain genetic test scores. The goal is to find out who can saf…
Matched conditions: HORMONE RECEPTOR-POSITIVE/HER2 NEGATIVE BREAST CANCER
Sponsor: Gangnam Severance Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Can a potato starch supplement ease cancer drug side effects?
Knowledge-focused Not yet recruitingThis study will track gut microbiome changes in 12 women with hormone receptor-positive breast cancer starting Verzenio (abemaciclib) therapy. Participants will take either a resistant potato starch supplement or a placebo, and provide stool samples and symptom questionnaires rem…
Matched conditions: HORMONE RECEPTOR-POSITIVE/HER2 NEGATIVE BREAST CANCER
Phase: NA • Sponsor: University of Vermont Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC