HIGH GRADE B-CELL LYMPHOMA WITH MYC AND BCL2 OR BCL6 REARRANGEMENTS
Clinical trials for HIGH GRADE B-CELL LYMPHOMA WITH MYC AND BCL2 OR BCL6 REARRANGEMENTS explained in plain language.
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New hope for aggressive lymphoma: targeted therapy before chemo shows promise
Disease control Recruiting nowThis study tests a two-step treatment for people with a fast-growing type of lymphoma that is hard to treat. First, a targeted drug (loncastuximab tesirine) plus rituximab is given to attack cancer cells directly. Then, standard chemotherapy (DA-EPOCH-R) is used to kill remaining…
Matched conditions: HIGH GRADE B-CELL LYMPHOMA WITH MYC AND BCL2 OR BCL6 REARRANGEMENTS
Phase: PHASE2 • Sponsor: Joseph Tuscano • Aim: Disease control
Last updated May 11, 2026 20:52 UTC
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Vitamin c boost: could high doses help chemo fight tough lymphomas?
Disease control Recruiting nowThis phase 2 trial tests whether adding high-dose vitamin C to standard chemotherapy can improve outcomes for people with lymphoma that has returned or not responded to treatment, as well as for those with related blood disorders like chronic myelomonocytic leukemia. About 80 adu…
Matched conditions: HIGH GRADE B-CELL LYMPHOMA WITH MYC AND BCL2 OR BCL6 REARRANGEMENTS
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 06, 2026 16:03 UTC
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Immune boosting cells show promise in fighting blood cancers after transplant
Disease control Recruiting nowThis study tests whether giving patients personalized natural killer (NK) cells after chemotherapy and a cord blood transplant can help kill remaining cancer cells and reduce complications. It includes 100 adults with various blood cancers like leukemia, lymphoma, or multiple mye…
Matched conditions: HIGH GRADE B-CELL LYMPHOMA WITH MYC AND BCL2 OR BCL6 REARRANGEMENTS
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 29, 2026 15:02 UTC
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Gene study could unlock secrets of aggressive lymphoma
Knowledge-focused Recruiting nowThis study is for people with certain types of aggressive lymphoma (DLBCL or high-grade B-cell lymphoma) who have changes in the MYC gene. Researchers want to learn how these genetic changes relate to the immune environment around the tumor and how they affect treatment success. …
Matched conditions: HIGH GRADE B-CELL LYMPHOMA WITH MYC AND BCL2 OR BCL6 REARRANGEMENTS
Sponsor: Fondazione Italiana Linfomi - ETS • Aim: Knowledge-focused
Last updated May 13, 2026 16:03 UTC