HIGH GRADE B-CELL LYMPHOMA WITH MYC AND BCL2 OR BCL6 REARRANGEMENTS
Clinical trials for HIGH GRADE B-CELL LYMPHOMA WITH MYC AND BCL2 OR BCL6 REARRANGEMENTS explained in plain language.
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New hope for aggressive lymphoma: targeted therapy plus chemo shows promise
Disease control Recruiting nowThis study tests whether a targeted drug (loncastuximab tesirine) plus rituximab, followed by standard chemotherapy, can improve outcomes for people with high-risk diffuse large B-cell lymphoma. About 24 adults with untreated, aggressive subtypes will receive this combination. Th…
Matched conditions: HIGH GRADE B-CELL LYMPHOMA WITH MYC AND BCL2 OR BCL6 REARRANGEMENTS
Phase: PHASE2 • Sponsor: Joseph Tuscano • Aim: Disease control
Last updated Jun 15, 2026 19:03 UTC
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Vitamin c boost: could high doses help chemo fight tough blood cancers?
Disease control Recruiting nowThis study tests whether adding high-dose vitamin C (ascorbic acid) to standard chemotherapy can help kill cancer cells better in people with certain blood cancers that have returned or not responded to treatment. It includes adults with relapsed or refractory lymphoma, clonal cy…
Matched conditions: HIGH GRADE B-CELL LYMPHOMA WITH MYC AND BCL2 OR BCL6 REARRANGEMENTS
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 15, 2026 19:02 UTC
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Immune boosting NK cells aim to stop blood cancer relapse after transplant
Disease control Recruiting nowThis study tests whether giving patients their own personalized natural killer (NK) cells after chemotherapy and a cord blood transplant can help kill leftover cancer cells and reduce the risk of graft-versus-host disease. It includes 100 adults with various blood cancers like le…
Matched conditions: HIGH GRADE B-CELL LYMPHOMA WITH MYC AND BCL2 OR BCL6 REARRANGEMENTS
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 15, 2026 18:55 UTC
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Gene study could unlock secrets of aggressive lymphoma
Knowledge-focused Recruiting nowThis study looks at how changes in the MYC gene affect people with diffuse large B-cell lymphoma or high-grade B-cell lymphoma. Researchers will study tissue samples from 200 patients to understand how these gene changes relate to the immune environment around the tumor. The goal…
Matched conditions: HIGH GRADE B-CELL LYMPHOMA WITH MYC AND BCL2 OR BCL6 REARRANGEMENTS
Sponsor: Fondazione Italiana Linfomi - ETS • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:03 UTC