HEPATIC ENCEPHALOPATHY (HE)
Clinical trials for HEPATIC ENCEPHALOPATHY (HE) explained in plain language.
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Pig liver machine tested as lifeline for patients in liver failure
Disease control Not yet recruitingThis is a first-in-human safety study testing a new device that temporarily supports failing livers. The device connects a patient's blood to a genetically engineered pig liver, aiming to filter toxins and perform liver functions. The trial will enroll up to 20 adults with severe…
Matched conditions: HEPATIC ENCEPHALOPATHY (HE)
Phase: PHASE1 • Sponsor: eGenesis, INC • Aim: Disease control
Last updated Mar 16, 2026 15:24 UTC
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Liver shunt brain fog: can a common pill block it?
Prevention Not yet recruitingThis study tests if adding ursodeoxycholic acid (a bile acid pill) to the standard laxative treatment (lactulose) can better prevent brain fog (hepatic encephalopathy) after a liver shunt procedure (TIPS). It will involve 270 adults with severe liver cirrhosis who are getting the…
Matched conditions: HEPATIC ENCEPHALOPATHY (HE)
Phase: NA • Sponsor: West China Hospital • Aim: Prevention
Last updated Mar 27, 2026 12:40 UTC
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Scientists hunt for clues to Liver-Related brain fog in blood and gut
Knowledge-focused Not yet recruitingThis study aims to understand why some people with liver cirrhosis develop brain fog, known as hepatic encephalopathy. Researchers will compare 32 patients with and without this brain fog by analyzing their blood proteins and gut bacteria. The goal is to find biological clues tha…
Matched conditions: HEPATIC ENCEPHALOPATHY (HE)
Sponsor: The First Affiliated Hospital with Nanjing Medical University • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC