HEPATIC ENCEPHALOPATHY (HE)
Clinical trials for HEPATIC ENCEPHALOPATHY (HE) explained in plain language.
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Pig liver trial offers hope for liver failure patients
Disease control Not yet recruitingThis early-stage study tests a genetically-modified pig liver (EGEN-5784) used outside the body with a special device to temporarily support liver function in 20 adults with acute-on-chronic liver failure. Participants are not eligible for a transplant. The goal is to check safet…
Matched conditions: HEPATIC ENCEPHALOPATHY (HE)
Phase: PHASE1 • Sponsor: eGenesis, INC • Aim: Disease control
Last updated May 17, 2026 05:05 UTC
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Could a common bile acid pill prevent brain fog after liver shunt surgery?
Prevention Not yet recruitingThis study tests whether adding a bile acid pill (UDCA) to standard treatment can prevent serious brain confusion (hepatic encephalopathy) after a liver shunt procedure called TIPS. About 270 adults with cirrhosis will receive either UDCA plus lactulose or lactulose alone for 3 m…
Matched conditions: HEPATIC ENCEPHALOPATHY (HE)
Phase: NA • Sponsor: West China Hospital • Aim: Prevention
Last updated May 17, 2026 05:05 UTC
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Gut bacteria clues could unlock liver brain fog mystery
Knowledge-focused Not yet recruitingThis study looks at 32 adults with liver cirrhosis to see if their blood proteins and gut bacteria differ between those who develop hepatic encephalopathy (brain fog) and those who don't. By identifying unique patterns, researchers hope to better understand the condition and guid…
Matched conditions: HEPATIC ENCEPHALOPATHY (HE)
Sponsor: The First Affiliated Hospital with Nanjing Medical University • Aim: Knowledge-focused
Last updated May 14, 2026 12:02 UTC