HEMATOLOGIC MALIGNANCIES
Clinical trials for HEMATOLOGIC MALIGNANCIES explained in plain language.
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New transplant approach opens donor options for blood cancer patients
Disease control CompletedThis study tested a bone marrow transplant using donors who are not perfectly matched or first-degree relatives, for people with blood cancers. The goal was to see if this approach could control the cancer with acceptable side effects like graft-versus-host disease. 87 participan…
Matched conditions: HEMATOLOGIC MALIGNANCIES
Phase: PHASE1, PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins • Aim: Disease control
Last updated May 16, 2026 23:47 UTC
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New Blood-Cleansing method boosts transplant success in sensitized patients
Disease control CompletedThis study looked at 50 patients who needed a stem cell transplant from a partially matched donor but had antibodies that could attack the donor cells. Before transplant, they received a blood purification treatment called protein A immunoadsorption to remove those antibodies. Th…
Matched conditions: HEMATOLOGIC MALIGNANCIES
Sponsor: Ting YANG • Aim: Disease control
Last updated May 16, 2026 23:38 UTC
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Blood cancer Drug's Long-Term safety checked in small Follow-Up study
Disease control CompletedThis study looked at the long-term safety of an oral chemotherapy drug (azacitidine) in 5 adults with blood cancers who had already taken it in earlier studies. Researchers tracked side effects and survival over time. The goal was to see if continuing the drug was safe and benefi…
Matched conditions: HEMATOLOGIC MALIGNANCIES
Phase: PHASE2 • Sponsor: Celgene • Aim: Disease control
Last updated May 16, 2026 23:36 UTC
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New drug shows promise in preventing transplant complications for blood cancer patients
Disease control CompletedThis study tested whether the drug tildrakizumab can help prevent graft-versus-host disease (GVHD) in people receiving a stem cell transplant for blood cancers. GVHD occurs when donor cells attack the patient's body. The trial included 51 adults with blood cancers like leukemia. …
Matched conditions: HEMATOLOGIC MALIGNANCIES
Phase: PHASE2 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated May 12, 2026 13:39 UTC
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New drug cocktail shows promise for Hard-to-Treat lymphomas
Disease control CompletedThis study tested a new combination of three drugs (VIP152, venetoclax, and prednisone) in 8 adults with aggressive blood cancers like diffuse large B-cell lymphoma that had returned or not responded to prior treatments. The goal was to find a safe dose and see if the combination…
Matched conditions: HEMATOLOGIC MALIGNANCIES
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 26, 2026 20:01 UTC
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COVID-19 era shifted fungal infection patterns in transplant patients, study finds
Knowledge-focused CompletedThis study looked back at medical records of 60 adults with blood cancers who had a stem cell transplant and later developed a rare fungal infection called mucormycosis. Researchers compared cases before and during the COVID-19 pandemic to see how the virus, new diagnostic tools,…
Matched conditions: HEMATOLOGIC MALIGNANCIES
Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Knowledge-focused
Last updated May 16, 2026 23:37 UTC
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Planning ahead: hospital program helps older blood cancer patients document their care wishes
Knowledge-focused CompletedThis study tested a program to help older patients (age 60+) with blood cancers plan their future medical care while in the hospital. The program focused on completing advance directives, like naming a healthcare proxy. Researchers wanted to see if the program was practical and h…
Matched conditions: HEMATOLOGIC MALIGNANCIES
Phase: NA • Sponsor: University of Rochester • Aim: Knowledge-focused
Last updated May 07, 2026 18:41 UTC