HEART TRANSPLANT FAILURE AND REJECTION
Clinical trials for HEART TRANSPLANT FAILURE AND REJECTION explained in plain language.
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Can a smart dosing tool prevent heart transplant rejection in children?
Disease control CompletedThis study tests a personalized dosing tool for tacrolimus, an immunosuppressant drug given to children after a heart transplant to prevent organ rejection. The tool uses a computer model that considers each child's age, kidney function, and other medications to calculate the bes…
Matched conditions: HEART TRANSPLANT FAILURE AND REJECTION
Phase: NA • Sponsor: University of Utah • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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Can a new drug combo shield young hearts from transplant complications?
Disease control CompletedThis trial tests whether a combination of everolimus and low-dose tacrolimus is better than the standard tacrolimus plus mycophenolate mofetil at preventing serious long-term complications in children who have had a heart transplant. The study will follow 211 participants from 25…
Matched conditions: HEART TRANSPLANT FAILURE AND REJECTION
Phase: PHASE3 • Sponsor: Boston Children's Hospital • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
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New blood test could replace painful heart biopsies for transplant patients
Diagnosis CompletedThis study tested a new blood test called HEARTBiT that uses 9 RNA markers to detect acute rejection in heart transplant patients. Currently, rejection is found through frequent, invasive heart biopsies. The test was developed using samples from 150 patients and will be evaluated…
Matched conditions: HEART TRANSPLANT FAILURE AND REJECTION
Sponsor: University of British Columbia • Aim: Diagnosis
Last updated Jun 27, 2026 12:29 UTC
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Can a simple body scan predict heart transplant success?
Knowledge-focused CompletedThis study tested whether a device that measures body composition (bioelectrical impedance spectroscopy) can help predict complications after a heart transplant. Researchers followed 69 adult heart transplant patients for one year, tracking changes in muscle and fat. The goal was…
Matched conditions: HEART TRANSPLANT FAILURE AND REJECTION
Sponsor: Baylor Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC