HEALTHY VOLUNTEERS (HV)

This study is testing a new blood test that looks for specific DNA changes (called epigenetic changes) to help diagnose breast cancer. Researchers will collect blood samples from 450 people, including those with breast cancer, healthy volunteers, and others, and follow them for a…

This first-in-human trial tests the safety and tolerability of a single dose of the experimental drug ZE66-0205 in healthy adults aged 18 to 55. Researchers will also measure how the drug moves through the body and how it affects MALT1 levels in blood cells. Participants are rand…

This trial explores whether shining low-level light on the scalp—a technique called transcranial photobiomodulation—can change brain activity and improve fine motor skills like finger tapping. Twenty healthy young adults will receive different light pulse frequencies (continuous,…

This study explores whether shining near-infrared light on the scalp — a technique called transcranial photobiomodulation — can change how the brain controls movement. Twenty healthy adults aged 18 to 35 will receive light at different pulse frequencies (continuous, 10 Hz, 40 Hz,…

This early-phase study uses PET/CT brain scans to see how much of a single dose of LG-0317 tablets binds to serotonin transporters (SERT) in the brains of healthy men aged 18 to 45. Researchers will also measure drug levels in the blood and monitor for side effects. The goal is t…

This Phase 1 study tests whether a liquid containing exosomes from human umbilical cord cells is safe when applied to healthy skin. Ten healthy adults receive the exosome liquid on one small skin area and a placebo liquid on another. Researchers monitor for redness, swelling, itc…

This early-phase trial will test the safety and tolerability of a new drug called KR25102 in 83 healthy adults in China. Participants will receive either a single dose or multiple daily doses of the drug or a placebo. The main goal is to check for side effects and understand how …

This study checks if sticky surface electrodes can measure muscle signals as well as standard needle electrodes. Thirty healthy adults will have their leg muscle activity recorded with both methods during a one-hour session. The goal is to see if the less invasive sticker method …

This study looks at how two common drugs, rifampin and itraconazole, change the levels of MDR-001 in the body. It involves 28 healthy Chinese adults who will take MDR-001 alone and then with one of the other drugs. The goal is to gather safety and drug-level data, not to treat an…

This study tests whether a 6-month sleep education program, led by an occupational health nurse, can improve sleep duration in healthcare workers who work 12-hour alternating day-night shifts. 160 nurses and nursing assistants will be enrolled. The program includes an initial sle…