HEALTHY VOLUNTEER STUDY

This early-phase study looks at how heat stress changes kidney function in 28 healthy, fit volunteers. Researchers want to understand the body's chemical responses and whether taking vitamin B3 (niacinamide) can influence those changes. The goal is to gather knowledge, not to tre…

This early-stage study looks at how a single dose of an experimental hepatitis C drug combination (bemnifosbuvir and ruzasvir) behaves in people with severe kidney or liver impairment compared to healthy volunteers. About 28 adults will participate to measure drug levels and safe…

This study looks at how a new experimental drug combination (BEM/RZR) changes the levels of common opiate withdrawal medications (buprenorphine/naloxone or methadone) in the blood. It involves 32 healthy volunteers who are already on stable therapy for opiate withdrawal. The goal…

This study looks at how a protein called NaV1.8, found in pain-sensing nerves, contributes to different kinds of pain. Healthy volunteers receive tiny, safe doses of a drug that blocks NaV1.8 directly into their skin, then undergo brief pain tests (like heat, cold, or pressure). …

This study aims to safely expose 72 healthy adults to the bacteria that cause whooping cough. Participants will not receive antibiotics right away, allowing researchers to see how the body naturally clears the infection over up to 6 weeks. The goal is to learn about the bacteria'…

This study looks at whether a simple, non-invasive vibration treatment can prevent muscle weakening when a leg is immobilized. 42 healthy adults aged 18-45 will have one leg in a cast for 3 days. Some will receive daily vibration therapy to see if it helps maintain muscle strengt…

This study looks at how gentle touch on different parts of the ear changes brain activity in healthy adults. Researchers will use a special cap with infrared light sensors to measure brain responses while stimulating the ear with soft plastic filaments. The goal is to understand …