HARM REDUCTION
Clinical trials for HARM REDUCTION explained in plain language.
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New study offers e-cigarettes and quit-smoking pills to 6,000 hard-to-treat smokers
Disease control Not yet recruitingThis study looks at whether e-cigarettes or a medication called cytisine can help people who still smoke despite trying standard treatments like nicotine patches and counseling. About 6,000 adults who smoke at least 5 cigarettes a day will be randomly given either an e-cigarette …
Matched conditions: HARM REDUCTION
Phase: NA • Sponsor: Centre for Addiction and Mental Health • Aim: Disease control
Last updated May 01, 2026 15:57 UTC
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New tool aims to prevent opioid overdose during dose tapering
Prevention Not yet recruitingThis study tests a clinical decision support tool that reminds doctors to follow CDC guidelines when reducing opioid doses in patients. The goal is to lower the risk of withdrawal, overdose, and poisoning. About 200,000 primary care patients will take part, and researchers will c…
Matched conditions: HARM REDUCTION
Sponsor: University of Colorado, Denver • Aim: Prevention
Last updated May 01, 2026 20:12 UTC
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New alert aims to curb opioid overuse in 200,000 patients
Knowledge-focused Not yet recruitingThis study tests a computer alert that notifies doctors when a patient is about to move from short-term to long-term opioid use. The goal is to encourage doctors to review the patient's pain and risks before prescribing more opioids. Over 200,000 patients will take part, and rese…
Matched conditions: HARM REDUCTION
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated May 01, 2026 20:12 UTC
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Can a phone app help people in supportive housing stay stable?
Knowledge-focused Not yet recruitingThis study will test if a technology-based tool is helpful and easy to use for people living in supportive housing who also have substance use issues. About 25 residents and staff will try the tool, which includes videos and rewards, for two weeks. The goal is to see if it improv…
Matched conditions: HARM REDUCTION
Phase: NA • Sponsor: Oregon Research Behavioral Intervention Strategies, Inc. • Aim: Knowledge-focused
Last updated May 01, 2026 15:59 UTC