GVHD
Clinical trials for GVHD explained in plain language.
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New drug combo shows promise in preventing transplant complications
Disease control CompletedThis early-stage study tested whether adding a drug called BMS-986004 to standard immune-suppressing medicine could help prevent acute graft-versus-host disease (GVHD) in 45 adults with blood cancers or disorders receiving a stem cell transplant. GVHD occurs when donor immune cel…
Matched conditions: GVHD
Phase: PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Jun 16, 2026 22:20 UTC
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New drug shows promise in controlling transplant complications
Disease control CompletedThis study tested a new drug called EQ001 in 30 people who developed acute graft-versus-host disease (aGVHD) after a stem cell transplant. aGVHD is a serious condition where donor immune cells attack the patient's body. The goal was to see if EQ001 is safe and can help control th…
Matched conditions: GVHD
Phase: PHASE1, PHASE2 • Sponsor: Biocon Limited • Aim: Disease control
Last updated Jun 15, 2026 19:04 UTC
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New drug combo may reduce severe transplant complications in blood cancer patients
Disease control CompletedThis study tested whether a combination of two drugs, cyclophosphamide and abatacept, could lower the risk of chronic graft-versus-host disease (GVHD) after a stem cell transplant for high-risk blood cancers. GVHD happens when donor cells attack the patient's body. The trial enro…
Matched conditions: GVHD
Phase: PHASE2 • Sponsor: Dimitrios Tzachanis, MD PhD • Aim: Disease control
Last updated Jun 15, 2026 19:02 UTC
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New drug combo may prevent deadly transplant complication
Disease control CompletedThis study tested a new drug combination (pacritinib, sirolimus, and tacrolimus) to prevent graft-versus-host disease (GVHD) in 40 people receiving stem cell transplants for blood cancers. GVHD occurs when donor cells attack the patient's body. The approach aims to reduce this ri…
Matched conditions: GVHD
Phase: PHASE1, PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Jun 15, 2026 18:57 UTC
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New drug cocktail shows promise in preventing transplant complications
Disease control CompletedThis study tested whether a combination of two drugs, cyclophosphamide and bortezomib (CyBor), could prevent graft-versus-host disease (GVHD) in 23 adults with blood cancers who received a stem cell transplant. GVHD is a serious condition where donor cells attack the patient's bo…
Matched conditions: GVHD
Phase: PHASE2 • Sponsor: NYU Langone Health • Aim: Disease control
Last updated Jun 12, 2026 12:06 UTC
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Blood test may predict deadly transplant complication
Knowledge-focused CompletedThis study tested whether counting certain cells in the blood before a stem cell transplant can predict the risk of acute graft-versus-host disease (GVHD), a serious complication. Researchers enrolled 50 adults receiving their first transplant for blood cancer. The goal was to se…
Matched conditions: GVHD
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:51 UTC
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Scientists test designer immune molecules in autoimmune diseases
Knowledge-focused CompletedThis study looked at whether specially engineered versions of a natural immune protein (IL-2) can selectively boost regulatory T cells, which help calm the immune system. Researchers took blood samples from 67 people with various autoimmune or inflammatory conditions and tested t…
Matched conditions: GVHD
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 08, 2026 13:09 UTC