GRAFT VS HOST DISEASE

This study is testing a method to process stem cell transplants for patients with a serious blood disorder called myelodysplastic syndrome (MDS). The goal is to reduce a common and dangerous complication called graft-versus-host disease (GVHD), where the donor's immune cells atta…

This study provides continued access to the cancer drug ibrutinib for patients who benefited from it in previous clinical trials but cannot obtain it through regular commercial channels. It allows about 300 patients with various blood cancers or solid tumors to keep receiving the…

This study is testing if adding a drug called vorinostat to standard medications can better prevent graft-versus-host disease (GVHD) in children and young adults getting a bone marrow transplant for blood cancers. GVHD is a serious complication where the donor's immune cells atta…

This study is testing a new combination of three drugs to prevent a dangerous complication called graft-versus-host disease (GVHD) after a half-matched stem cell transplant for blood cancers. The trial involves 27 adults receiving a transplant from a partially matched family dono…

This study is testing a new experimental imaging device called MSOT. It uses light and sound waves to take pictures of inflammation through the skin in people with Crohn's disease, colitis, or graft-versus-host disease. The main goal is to check if the device is safe and if its i…

This study is testing if a virtual group support program can help adults who developed a serious complication called chronic Graft-Versus-Host Disease (GVHD) after a stem cell transplant. The program aims to improve their quality of life, help them cope with symptoms, and manage …

This study is testing whether a specific type of ultraviolet light treatment (UVA-1) can improve symptoms and daily life for people with conditions that cause skin hardening, like scleroderma and morphea. Researchers will give 30 light therapy sessions to 30 participants and meas…

This study is testing whether a group-based support program called Horizons is practical and helpful for adults living with chronic graft-versus-host disease, a serious complication of stem cell transplants. The program aims to teach coping skills to improve quality of life. Rese…

This study aims to develop better tools to measure whether treatments are working for chronic Graft-versus-Host Disease (GVHD), a serious complication that can occur after stem cell transplants. Researchers are following 383 patients who have started new treatments for chronic GV…

This study aims to understand how the immune system works in people with inflammatory bowel disease (IBD), graft-versus-host disease (GVHD), and other related conditions. Researchers will collect blood and tissue samples from about 1,000 participants, including patients and healt…