GRADE IV GLIOMA
Clinical trials for GRADE IV GLIOMA explained in plain language.
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Brain tumor drug safety under scrutiny: temozolomide liver risk study launched
Disease control Recruiting nowThis study looks at how safe and effective temozolomide (brand name Amitzo) is for people with aggressive brain tumors (grade III and IV gliomas). Researchers are tracking 100 patients to see how often liver injury occurs and to monitor other side effects. The goal is to better u…
Matched conditions: GRADE IV GLIOMA
Sponsor: NanoAlvand • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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Brain cancer fog: could a common antidepressant boost thinking?
Symptom relief Recruiting nowThis study tests whether escitalopram, a common antidepressant, can improve thinking and memory problems in people with a severe type of brain tumor called grade IV glioma. Up to 85% of these patients struggle with cognitive issues from the tumor or its treatment. The study will …
Matched conditions: GRADE IV GLIOMA
Phase: PHASE2 • Sponsor: University of Nebraska • Aim: Symptom relief
Last updated Jun 27, 2026 12:09 UTC
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New pill targets brain tumor metabolism in early trial
Knowledge-focused Recruiting nowThis early phase 1 trial is testing an oral drug called DSP-0390 in 20 people with IDH-mutant gliomas who are scheduled for tumor removal surgery. The goal is to see how much of the drug gets into the brain tumor and blood, and whether it affects cholesterol-related pathways. Par…
Matched conditions: GRADE IV GLIOMA
Phase: EARLY_PHASE1 • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC