Grade 2 and 3 late xerostomia caused by radiotherapy for cancers of the upper aerodigestive tract, excluding the parotid glands
Clinical trials for Grade 2 and 3 late xerostomia caused by radiotherapy for cancers of the upper aerodigestive tract, excluding the parotid glands explained in plain language.
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Gene therapy could restore saliva flow in dry mouth sufferers
Disease control OngoingThis study tests a gene therapy (AAV2-hAQP1) injected into the saliva glands to see if it can safely increase saliva production in people with long-term dry mouth after radiation for head and neck cancer. About 276 adults who completed radiation at least 3 years ago will receive …
Matched conditions: GRADE 2 AND 3 LATE XEROSTOMIA CAUSED BY RADIOTHERAPY FOR CANCERS OF THE UPPER AERODIGESTIVE TRACT, EXCLUDING THE PAROTID GLANDS
Phase 2 • Sponsor: MeiraGTx, LLC • Aim: Disease control
Last updated Jul 26, 2026 00:00 UTC
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Gene therapy for radiation dry mouth tracked long-term
Disease control By invitation onlyThis study follows adults who previously received a gene therapy (AAV2-hAQP1) for dry mouth caused by radiation treatment for head and neck cancers. Researchers will check for side effects and how well the therapy works over time. About 276 people who already got the therapy in a…
Matched conditions: GRADE 2 AND 3 LATE XEROSTOMIA CAUSED BY RADIOTHERAPY FOR CANCERS OF THE UPPER AERODIGESTIVE TRACT, EXCLUDING THE PAROTID GLANDS
Phase 2 • Sponsor: MeiraGTx, LLC • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC