Gene therapy for radiation dry mouth tracked long-term

NCT ID NCT06544798

ENROLLING_BY_INVITATION Disease control Sponsor: MeiraGTx, LLC Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows adults who previously received a gene therapy (AAV2-hAQP1) for dry mouth caused by radiation treatment for head and neck cancers. Researchers will check for side effects and how well the therapy works over time. About 276 people who already got the therapy in an earlier study will take part.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Alleghany General Hospital

    Pittsburgh, Pennsylvania, 15212, United States

  • Atrium Health

    Charlotte, North Carolina, 28209, United States

  • Banner MD Anderson Cancer Center

    Gilbert, Arizona, 85234, United States

  • Erie County Medical Center

    Buffalo, New York, 14215, United States

  • Miami Cancer Institute at Baptist Health South Florida

    Miami, Florida, 33176, United States

  • Shirley and Jim Fielding Northeast Cancer Centre - Health Sciences North

    Greater Sudbury, Ontario, P3E 5J1, Canada

  • University of Iowa

    Iowa City, Iowa, 52242, United States

  • University of Missouri

    Columbia, Missouri, 65212, United States

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