GLIOMAS
Clinical trials for GLIOMAS explained in plain language.
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Brain cancer chemo delivered directly: a safety first
Disease control CompletedThis early-stage study tested whether it is safe to deliver the chemotherapy drug topotecan directly into the brain over several days for people with recurrent high-grade gliomas (a type of aggressive brain cancer). Five participants received the treatment through a special infus…
Matched conditions: GLIOMAS
Phase: PHASE1 • Sponsor: Columbia University • Aim: Disease control
Last updated Jun 16, 2026 22:37 UTC
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Immunotherapy drug shows promise for tough brain cancers
Disease control CompletedThis study tested the drug nivolumab in 35 adults with a type of brain tumor called IDH mutant glioma that had come back or worsened after prior treatment. The goal was to see if the drug could shrink the tumors. Nivolumab is an immunotherapy that helps the immune system fight ca…
Matched conditions: GLIOMAS
Phase: PHASE2 • Sponsor: Fabio Iwamoto, MD • Aim: Disease control
Last updated Jun 08, 2026 13:07 UTC
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450 brain tumor patients reveal key survival clues
Knowledge-focused CompletedThis study looked back at 450 people who had surgery for a rare type of brain tumor (cerebellar glioma). Researchers wanted to see if where the tumor was located and its genetic makeup could predict how much of the tumor could be safely removed and how long patients lived. The go…
Matched conditions: GLIOMAS
Sponsor: West China Hospital • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:04 UTC