Immunotherapy drug shows promise for Hard-to-Treat brain tumors

NCT ID NCT03557359

First seen Nov 03, 2025 · Last updated May 15, 2026 · Updated 29 times

Summary

This study tested the drug nivolumab in 35 adults with a type of brain tumor (glioma) that has an IDH mutation and came back after previous treatment. The goal was to see if the drug could shrink the tumors. Nivolumab is an immunotherapy that helps the immune system fight cancer, but it is not a cure and ongoing management is needed.

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Contacts and locations

Locations

  • Columbia University Medical Center

    New York, New York, 10032, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Miami Cancer Center

    Miami, Florida, 33176, United States

  • Weill Cornell Medical College

    New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.