GLIOMAS
Clinical trials for GLIOMAS explained in plain language.
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Immunotherapy drug shows promise for tough brain cancers
Disease control CompletedThis phase 2 trial tested the immunotherapy drug nivolumab (Opdivo) in 35 adults with recurrent or progressive IDH mutant gliomas that had been previously treated with alkylating agents. The main goal was to see if the drug could shrink tumors. The study is now complete, and resu…
Matched conditions: GLIOMAS
Phase: PHASE2 • Sponsor: Fabio Iwamoto, MD • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Brain tumor chemo delivered by pump shows promise in tiny safety trial
Disease control CompletedThis early-phase study tested whether pumping the chemotherapy drug topotecan directly into the brain is safe for people with recurrent high-grade gliomas (aggressive brain tumors). Only 5 patients took part, and the main goal was to find a safe dose. The drug was delivered conti…
Matched conditions: GLIOMAS
Phase: PHASE1 • Sponsor: Columbia University • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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450 brain tumor patients reveal key survival clues
Knowledge-focused CompletedThis study looked back at 450 people who had surgery for a rare type of brain tumor (cerebellar glioma). Researchers wanted to see if where the tumor was located and its genetic makeup could predict how much of the tumor could be safely removed and how long patients lived. The go…
Matched conditions: GLIOMAS
Sponsor: West China Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC