GERM CELL TUMOR
Clinical trials for GERM CELL TUMOR explained in plain language.
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New hope for kids with rare cancer: drug combo shows promise
Disease control CompletedThis study tested a new combination of the drug sirolimus plus chemotherapy (nab-paclitaxel, ifosfamide, and carboplatin) in 32 children with recurrent or treatment-resistant yolk sac tumor. The goal was to see if the combo could shrink tumors and improve survival. The study is c…
Matched conditions: GERM CELL TUMOR
Phase: PHASE2, PHASE3 • Sponsor: Shandong First Medical University • Aim: Disease control
Last updated Jun 16, 2026 12:54 UTC
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Immune cells engineered to fight rare testicular cancer show promise in early trial
Disease control CompletedThis study tested a new treatment for adults with a rare type of testicular cancer called nonseminomatous germ cell tumors. The treatment uses the patient's own immune cells (T cells) that are modified in a lab to recognize and attack cancer cells carrying a protein called CD30. …
Matched conditions: GERM CELL TUMOR
Phase: PHASE2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 15, 2026 19:06 UTC
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New combo therapy offers hope for kids with Tough-to-Treat yolk sac tumor
Disease control CompletedThis study tested a new combination of thalidomide and chemotherapy (nab-paclitaxel, gemcitabine, and epirubicin) in 20 children with yolk sac tumor that had come back or stopped responding to standard treatments. The goal was to see if this approach could shrink tumors or lower …
Matched conditions: GERM CELL TUMOR
Phase: PHASE2 • Sponsor: Shandong First Medical University • Aim: Disease control
Last updated Jun 15, 2026 19:02 UTC
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Immune cells injected directly into brain show promise for kids with tough tumors
Disease control CompletedThis early-stage study tested a new treatment for children and young adults with brain tumors that came back or didn't respond to standard therapy. Doctors took the patients' own immune cells, modified them to recognize a protein called EGFR on tumor cells, and injected them dire…
Matched conditions: GERM CELL TUMOR
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated Jun 15, 2026 18:57 UTC
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New stem cell approach offers hope for kids with relapsed cancers
Disease control CompletedThis study tested a new type of stem cell transplant in 23 children and young adults with cancers that came back or didn't respond to treatment. The approach uses a special cell filter to speed up immune recovery and reduce risks. The main goal was to see if the transplant was fe…
Matched conditions: GERM CELL TUMOR
Phase: PHASE1 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Jun 11, 2026 12:10 UTC