GENERALIZED MYASTHENIA GRAVIS

This study aims to monitor the long-term safety of efgartigimod, a medication for generalized myasthenia gravis (gMG), in children who participated in earlier trials. It will follow up to 12 young participants who received either intravenous or subcutaneous injections of the drug…

This study is testing whether ravulizumab, an intravenous medication, can help control symptoms of generalized myasthenia gravis in children aged 6 to 18. Researchers will measure how the drug works in the body and whether it improves muscle strength and daily activities. The stu…

This study is following up with people who have generalized myasthenia gravis (gMG) to see how safe and effective the drug zilucoplan is over a longer period. It is for 200 participants who have already completed a previous zilucoplan trial. The main goal is to monitor side effec…

This study is testing whether an investigational drug called ALXN1720 is safe and effective for adults with generalized myasthenia gravis, a chronic autoimmune disease that causes severe muscle weakness. About 261 participants will receive either the drug or a placebo for 26 week…

This study aims to check the long-term safety and side effects of repeated treatment cycles with the drug rozanolixizumab in children aged 2 and older who have generalized myasthenia gravis (gMG). It is an extension study for children who completed a previous trial, allowing them…

This study is testing whether weekly injections of an experimental drug called batoclimab can help adults with generalized myasthenia gravis (gMG), a chronic autoimmune disease that causes severe muscle weakness. Researchers are comparing two different doses of the drug against a…

This study is giving children with a rare autoimmune muscle-weakening disease an extra year of an experimental drug to check its long-term safety. It's open to kids aged 2 and up who finished a previous trial and whose doctors think they could benefit from continuing treatment. T…

This study is testing two new drugs, pozelimab and cemdisiran, to see if they can better control the muscle weakness and fatigue caused by generalized myasthenia gravis (gMG). It will involve about 288 adults with gMG to compare the effectiveness and safety of using the drugs tog…

This study is testing whether an intravenous drug called efgartigimod is effective and safe for adults with a specific, hard-to-treat form of generalized myasthenia Gravis (gMG). About 119 participants will be randomly assigned to receive either the drug or a placebo for part of …