New drug tested for long-term safety in kids with rare muscle weakness disease

NCT ID NCT05374590

ENROLLING_BY_INVITATION Disease control Sponsor: argenx Source: ClinicalTrials.gov ↗

First seen Nov 19, 2025 · Last updated Apr 25, 2026 · Updated 21 times

Summary

This study looks at the long-term safety of a drug called efgartigimod in children with generalized myasthenia gravis, a disease that causes muscle weakness. About 12 children who already took part in earlier studies will continue receiving the drug either through a vein or as a shot under the skin. The goal is to track side effects and see how the body reacts to the medicine over time.

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Contacts and locations

Locations

  • AP-HM- Hôpital de La Timone

    Marseille, 13005, France

  • Ann and Robert H Lurie Children's Hospital of Chicago - Main Hospital

    Chicago, Illinois, 60611, United States

  • Atrium Health Neurology Specialty Care

    Charlotte, North Carolina, 28207, United States

  • Centralny Szpital Kliniczny - Uniwersyteckie Centrum Kliniczne WUM

    Warsaw, 02-097, Poland

  • Childrens Hospital of Eastern Ontario

    Ottawa, K1H 8L1, Canada

  • Great Ormand Street Hospital for Children NHS Foundation Trust - Great Ormond Street Hospital - Pediatric Neurology

    London, WC1N 3JH, United Kingdom

  • Hadassah Medical Center- Ein Kerem

    Jerusalem, 9112001, Israel

  • Hospital Universitari i Politecnic La Fe de Valencia

    Valencia, 46026, Spain

  • Leids Universitair Medisch Centrum

    Leiden, 2333 ZA, Netherlands

  • Oxford University Hospitals NHS Foundation Trust - John Radcliffe Hospital Children's Hospital

    Oxford, OX3 9DU, United Kingdom

  • UZ Gent

    Ghent, 9000, Belgium

  • Universitair Ziekenhuis Antwerpen

    Edegem, 2650, Belgium

  • University of Virginia (UVA) Health - Developmental Pediatrics Clinic

    Charlottesville, Virginia, 22903, United States

  • Universitätsklinikum Essen

    Essen, 45147, Germany

  • Uniwersyteckie Centrum Kliniczne w Gdansku

    Gdansk, 80-211, Poland

  • Wielospecjalistyczna Poradnia Lekarska Synapsis

    Katowice, 40-123, Poland

Conditions

Explore the condition pages connected to this study.