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New drug trial offers hope for debilitating muscle disease

NCT ID NCT06517758

Recruiting now Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This study is testing an investigational drug called iptacopan to see if it can help control symptoms and improve daily life for adults with generalized myasthenia gravis (gMG). About 146 participants will take either iptacopan or a placebo pill for 6 months while continuing their standard treatments. The main goal is to see if the drug reduces symptoms like muscle weakness that affect activities like talking, swallowing, and moving.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

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Locations

  • Augusta University Georgia

    RECRUITING

    Augusta, Georgia, 30912, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • California Pacific Medical Center

    RECRUITING

    Sacramento, California, 94115, United States

    Contact Phone: •••-•••-••••

    Contact

  • Center for Neurological Disorders G

    RECRUITING

    Greenfield, Wisconsin, 53228-1321, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Central TX Neuro Consultants P A

    RECRUITING

    Round Rock, Texas, 78681, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Duke University Medical Center

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact Email: •••••@•••••

    Contact

  • Fullerton Neuro and Headache Ctr

    RECRUITING

    Fullerton, California, 92835, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hawaii Pacific Neuroscience LLC

    WITHDRAWN

    Honolulu, Hawaii, 96817, United States

  • Honor Health Research Institute

    RECRUITING

    Scottsdale, Arizona, 85258, United States

    Contact Email: •••••@•••••

    Contact

  • Mid Atlantic Epilepsy and Sleep Ctr

    RECRUITING

    Bethesda, Maryland, 20817-1807, United States

    Contact

  • Nerve and Muscle Center of Texas

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Email: •••••@•••••

    Contact

  • Neurology Offices Of South Florida

    WITHDRAWN

    Boca Raton, Florida, 33428, United States

  • Neuroscience Research Ctr

    WITHDRAWN

    Canton, Ohio, 44718, United States

  • Novartis Investigative Site

    RECRUITING

    Hefei, Anhui, 230001, China

  • Novartis Investigative Site

    RECRUITING

    Guangzhou, Guangdong, 510515, China

  • Novartis Investigative Site

    RECRUITING

    Shenzhen, Guangdong, 518053, China

  • Novartis Investigative Site

    RECRUITING

    Shijiazhuang, Hebei, 50030, China

  • Novartis Investigative Site

    RECRUITING

    Changsha, Hunan, 410008, China

  • Novartis Investigative Site

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    Suzhou, Jiangsu, 215004, China

  • Novartis Investigative Site

    RECRUITING

    Nanchang, Jiangxi, 330006, China

  • Novartis Investigative Site

    RECRUITING

    Xi'an, Shaanxi, 710075, China

  • Novartis Investigative Site

    RECRUITING

    Xianyang, Shaanxi, 712000, China

  • Novartis Investigative Site

    RECRUITING

    Beijing, 065001, China

  • Novartis Investigative Site

    RECRUITING

    Beijing, 100034, China

  • Novartis Investigative Site

    RECRUITING

    Beijing, 100730, China

  • Novartis Investigative Site

    RECRUITING

    Fujian, 350001, China

  • Novartis Investigative Site

    RECRUITING

    Jinan, 250012, China

  • Novartis Investigative Site

    RECRUITING

    Copenhagen, DK-2100, Denmark

  • Novartis Investigative Site

    RECRUITING

    Athens, 115 28, Greece

  • Novartis Investigative Site

    RECRUITING

    Chaïdári, 124 62, Greece

  • Novartis Investigative Site

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    Larissa, 411 10, Greece

  • Novartis Investigative Site

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    Pátrai, 265 04, Greece

  • Novartis Investigative Site

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    Thessaloniki, 54636, Greece

  • Novartis Investigative Site

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    Haifa, 3109601, Israel

  • Novartis Investigative Site

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    Jerusalem, 9112001, Israel

  • Novartis Investigative Site

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    Bologna, BO, 40139, Italy

  • Novartis Investigative Site

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    Florence, FI, 50134, Italy

  • Novartis Investigative Site

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    Genova, GE, 16132, Italy

  • Novartis Investigative Site

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    Milan, MI, 20133, Italy

  • Novartis Investigative Site

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    Palermo, PA, 90127, Italy

  • Novartis Investigative Site

    RECRUITING

    Palermo, PA, 90146, Italy

  • Novartis Investigative Site

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    Roma, RM, 00133, Italy

  • Novartis Investigative Site

    RECRUITING

    Roma, RM, 00135, Italy

  • Novartis Investigative Site

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    Roma, RM, 00189, Italy

  • Novartis Investigative Site

    RECRUITING

    Orbassano, TO, 10043, Italy

  • Novartis Investigative Site

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    Napoli, 80131, Italy

  • Novartis Investigative Site

    RECRUITING

    Narita, Chiba, 286-8520, Japan

  • Novartis Investigative Site

    RECRUITING

    Sapporo, Hokkaido, 0630005, Japan

  • Novartis Investigative Site

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    Nishinomiya, Hyōgo, 663 8501, Japan

  • Novartis Investigative Site

    RECRUITING

    Hanamaki, Iwate, 025-0082, Japan

  • Novartis Investigative Site

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    Sendai, Miyagi, 983 8520, Japan

  • Novartis Investigative Site

    RECRUITING

    Suita, Osaka, 5650871, Japan

  • Novartis Investigative Site

    RECRUITING

    Higashi-Matsuyama, Saitama, 355-0005, Japan

  • Novartis Investigative Site

    RECRUITING

    Shinjuku Ku, Tokyo, 160-0023, Japan

  • Novartis Investigative Site

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    Chiba, 260 8677, Japan

  • Novartis Investigative Site

    RECRUITING

    Fukuoka, 8128582, Japan

  • Novartis Investigative Site

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    Fukushima, 9601295, Japan

  • Novartis Investigative Site

    RECRUITING

    Hiroshima, 7348551, Japan

  • Novartis Investigative Site

    RECRUITING

    Lublin, Lublin Voivodeship, 20-064, Poland

  • Novartis Investigative Site

    RECRUITING

    Krakow, POL, 31-505, Poland

  • Novartis Investigative Site

    RECRUITING

    Katowice, Silesian Voivodeship, 40-650, Poland

  • Novartis Investigative Site

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    Bydgoszcz, 85-065, Poland

  • Novartis Investigative Site

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    Katowice, 40-689, Poland

  • Novartis Investigative Site

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    Krakow, 31-870, Poland

  • Novartis Investigative Site

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    Lublin, 20-410, Poland

  • Novartis Investigative Site

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    Poznan, 61-731, Poland

  • Novartis Investigative Site

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    Rzeszów, 35-055, Poland

  • Novartis Investigative Site

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    Warsaw, 01-684, Poland

  • Novartis Investigative Site

    RECRUITING

    Lisbon, 1349-019, Portugal

  • Novartis Investigative Site

    RECRUITING

    Lisbon, 1649-035, Portugal

  • Novartis Investigative Site

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    Porto, 4099-001, Portugal

  • Novartis Investigative Site

    RECRUITING

    Vila Nova de Gaia, 4434 502, Portugal

  • Novartis Investigative Site

    RECRUITING

    Gwangju, 61469, South Korea

  • Novartis Investigative Site

    RECRUITING

    Santiago Compostela, A Coruna, 15706, Spain

  • Novartis Investigative Site

    RECRUITING

    L'Hospitalet de Llobregat, Barcelona, 08907, Spain

  • Novartis Investigative Site

    RECRUITING

    Alicante, 03010, Spain

  • Novartis Investigative Site

    RECRUITING

    Barcelona, 08036, Spain

  • Novartis Investigative Site

    RECRUITING

    Lleida, 25198, Spain

  • Novartis Investigative Site

    RECRUITING

    Madrid, 28006, Spain

  • Novartis Investigative Site

    RECRUITING

    Málaga, 29010, Spain

  • Novartis Investigative Site

    RECRUITING

    Valencia, 46026, Spain

  • Novartis Investigative Site

    RECRUITING

    Inverness, Invernesshire, IV2 3RE, United Kingdom

  • Novartis Investigative Site

    WITHDRAWN

    Ilford, London, IG1 4HP, United Kingdom

  • Novartis Investigative Site

    RECRUITING

    Swinton, Manchester, M27 8FF, United Kingdom

  • Novartis Investigative Site

    RECRUITING

    Birmingham, West Midlands, B15 2TH, United Kingdom

  • Novartis Investigative Site

    WITHDRAWN

    Liverpool, L9 7LT, United Kingdom

  • Novartis Investigative Site

    RECRUITING

    London, SW17 0QT, United Kingdom

  • Novartis Investigative Site

    RECRUITING

    Southampton, SO16 6YD, United Kingdom

  • Ohio State University Medical Center

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact

  • Penn Presbyterian Medical Center

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Prairie Heart Institute

    RECRUITING

    Springfield, Illinois, 62769, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • SC3 Research Pasadena

    RECRUITING

    Pasadena, California, 91105, United States

    Contact Email: •••••@•••••

    Contact

  • Superior Associates in Research LLC

    WITHDRAWN

    Hialeah, Florida, 33012, United States

  • University of Chicago Medical Centr

    RECRUITING

    Chicago, Illinois, 60637, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Vanderbilt University Medical CenterX

    RECRUITING

    Nashville, Tennessee, 37221, United States

    Contact

Conditions

Explore the condition pages connected to this study.

GENERALIZED MYASTHENIA GRAVIS