FUNCTIONAL CONSTIPATION

This study looked at the long-term safety of the drug linaclotide in children aged 6 to 17 with functional constipation or irritable bowel syndrome with constipation (IBS-C). A total of 381 children who had already completed earlier studies took linaclotide for 24 or 52 weeks. Th…

This study tested a hands-on therapy called visceral osteopathy for people with functional constipation. 27 adults received either osteopathic manual therapy or standard dietary advice. The goal was to see if the manual therapy could improve bowel symptoms and quality of life bet…

This study tested whether a daily mix of a special fiber (guar gum) and a probiotic (Lacticaseibacillus rhamnosus GG) could help children with long-term constipation. Fifty-two children aged 4 to 16 took either the supplement plus diet advice or just diet advice for 12 weeks. Res…

This study tested whether a daily probiotic capsule (Bio-K+) could help adults with functional constipation have more complete and comfortable bowel movements. Over 12 weeks, 168 participants took either the probiotic or a placebo. Researchers tracked changes in bowel movement fr…

This study tested whether a daily probiotic supplement called Bacillus coagulans could improve constipation symptoms and gut bacteria in adults. Eighty participants took either the probiotic or a placebo for 12 weeks. The goal was to see if the probiotic could ease discomfort and…

This study tested a medicine called linaclotide in 19 babies and toddlers (6 months to under 2 years old) with long-term constipation. The goal was to see if it helps them have more bowel movements and softer stools, and to check for side effects. Children took the medicine as a …

This study tested a new, smaller bowel irrigation device called Navina Mini in 27 children and teens aged 3 to 17 with bowel problems like severe constipation or leakage. The goal was to see if the device is safe, easy to use, and improves bowel emptying and satisfaction. Results…