FOCAL EPILEPSY

This study is testing whether gentle electrical stimulation applied to the scalp can reduce the number and intensity of epileptic seizures. Researchers are enrolling 30 adults with epilepsy that hasn't been well-controlled by medications to try at-home stimulation sessions. The g…

This study is testing the long-term safety and effectiveness of an investigational drug called RAP-219 for adults with focal epilepsy that doesn't respond well to current medications. It follows 30 participants who have already completed a related short-term study to see how well…

This study is testing whether an investigational drug called BHV-7000 can help reduce seizures in adults with focal epilepsy that hasn't been controlled by other medications. About 390 participants will be randomly assigned to receive either one of two doses of BHV-7000 or a plac…

This study follows patients for up to two years to check the long-term safety and effectiveness of an experimental epilepsy drug called CB03-154. It includes 144 people with focal epilepsy who successfully finished an earlier trial. The goal is to see how well the drug controls s…

This study is testing if a small device implanted just under the scalp can safely predict when a seizure is about to happen in people with epilepsy that doesn't respond well to medication. The goal is to use these forecasts to help manage the condition and improve quality of life…

This study is testing whether an experimental drug called BHV-7000 can help reduce seizures in adults with focal epilepsy that hasn't responded well to existing medications. About 390 participants will receive either the drug or a placebo (inactive substance) in addition to their…

This study is testing a new type of flexible, high-density electrode grid used to map the brain during epilepsy surgery. The goal is to see if these new electrodes perform as well as or better than the standard ones at recording brain signals and identifying areas that cause seiz…

This study is testing whether a drug called butylphthalide can help improve memory and thinking problems in older adults who have epilepsy. 220 participants aged 60-85 with epilepsy and mild to moderate memory issues will take either the drug or a placebo pill for 48 weeks, while…

This study aims to better understand how severe epilepsy works in children's brains. Researchers will record detailed electrical activity from deep brain regions in 30 children already scheduled for a pre-surgery evaluation. The goal is to gather knowledge that could help design …

This study aims to understand how epileptic seizures start and progress by recording detailed brain activity from electrodes implanted in patients. Researchers will study 50 people with drug-resistant epilepsy who are already scheduled for this type of monitoring as part of their…