Brain recording study aims to personalize epilepsy therapy for kids

NCT ID NCT06453759

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will record brain activity from deep brain regions (the thalamus) in 30 children already undergoing epilepsy surgery evaluation. Researchers will place extra electrodes to measure how seizures spread and how brain areas connect. The goal is to find better targets for deep brain stimulation, which could help children whose seizures are not controlled by medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

additional electrodes placed in the thalamus during standard epilepsy monitoring

What this could lead to

If successful, this could lead to personalized deep brain stimulation targets for children with drug-resistant epilepsy, potentially improving seizure control.

What could go wrong

This is a small, early-stage observational study (30 participants) that aims to gather data, not test a treatment. It may not lead to immediate clinical benefits, and there is a small risk of bleeding from the extra electrodes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

focal epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Great Ormond Street Hospital for Children

    RECRUITING

    London, WC1N 3JH, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••