EXTENSIVE STAGE LUNG SMALL CELL CARCINOMA
Clinical trials for EXTENSIVE STAGE LUNG SMALL CELL CARCINOMA explained in plain language.
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New combo aims to outsmart Chemo-Resistant lung cancer
Disease control OngoingThis phase 2 trial tests whether adding berzosertib to standard chemotherapy (topotecan) helps people with relapsed small-cell lung cancer live longer without their cancer growing. About 104 participants will receive either the combo or topotecan alone. The goal is to see if berz…
Matched conditions: EXTENSIVE STAGE LUNG SMALL CELL CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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Brain radiation may be skipped in lung cancer: new trial tests safer monitoring
Disease control OngoingThis study tests whether using MRI brain scans alone to watch for cancer spread is as good as combining MRI with preventive brain radiation in people with small cell lung cancer. The goal is to see if avoiding radiation can reduce side effects and help patients live longer. About…
Matched conditions: EXTENSIVE STAGE LUNG SMALL CELL CARCINOMA
Phase: PHASE3 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated Jun 27, 2026 13:08 UTC
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New cocktail of drugs and radiation takes on tough lung cancer
Disease control OngoingThis study tests a combination of the PARP inhibitor olaparib, the immunotherapy durvalumab, chemotherapy (carboplatin and etoposide), and radiation in people with extensive-stage small cell lung cancer who haven't been treated yet. The goal is to see if this mix is safe and work…
Matched conditions: EXTENSIVE STAGE LUNG SMALL CELL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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New combo aims to keep lung cancer in check
Disease control OngoingThis phase II trial tests whether adding talazoparib to atezolizumab maintenance therapy works better than atezolizumab alone for people with a specific genetic marker (SLFN11-positive) and extensive-stage small cell lung cancer. About 100 participants will receive either the com…
Matched conditions: EXTENSIVE STAGE LUNG SMALL CELL CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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New cocktail of drugs targets Tough-to-Treat lung cancer
Disease control OngoingThis early-phase trial tests a combination of three drugs—tazemetostat, topotecan, and pembrolizumab—in 18 adults with small cell lung cancer that has returned after initial treatment. The goal is to find the safest dose and see if the combination can shrink or stabilize the canc…
Matched conditions: EXTENSIVE STAGE LUNG SMALL CELL CARCINOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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New combo aims to boost chemo for tough lung cancer
Disease control OngoingThis early-stage trial tests a new drug called LB-100 combined with standard chemotherapy and immunotherapy for people with untreated extensive-stage small cell lung cancer. The goal is to find the safest dose and see how well the combination works. Only 3 participants were enrol…
Matched conditions: EXTENSIVE STAGE LUNG SMALL CELL CARCINOMA
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Triple-Drug cocktail aims to keep lung cancer at bay
Disease control OngoingThis study tests a combination of three drugs—niraparib, temozolomide, and atezolizumab—in people with advanced solid tumors or extensive-stage small cell lung cancer. The goal is to find the best dose and see if the combination works better than atezolizumab alone as maintenance…
Matched conditions: EXTENSIVE STAGE LUNG SMALL CELL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC