ERBB2 GENE MUTATION
Clinical trials for ERBB2 GENE MUTATION explained in plain language.
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New drug cocktail targets Hard-to-Treat cancers
Disease control TerminatedThis early-stage trial tests the safety and best dose of the drug neratinib when combined with one of three other drugs (everolimus, palbociclib, or trametinib) in people with advanced solid tumors that have certain gene mutations or amplifications. The study enrolls 93 participa…
Matched conditions: ERBB2 GENE MUTATION
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jul 24, 2026 00:00 UTC
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Targeted drug poziotinib tested in rare lung cancer mutations
Disease control TerminatedThis phase II trial tested the drug poziotinib in 93 people with advanced non-small cell lung cancer that has specific changes in the EGFR or HER2 genes. The goal was to see if the drug could shrink tumors or stop them from growing. The study was terminated early, so results are …
Matched conditions: ERBB2 GENE MUTATION
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC