EARLY BREAST CANCER
Clinical trials for EARLY BREAST CANCER explained in plain language.
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New pill combo could replace chemo for some breast cancer patients
Disease control OngoingThis study tests whether a combination of two pills (letrozole and abemaciclib) works as well as standard chemotherapy before surgery in women with a common type of early breast cancer (HR-positive, HER2-negative) that is at high or intermediate risk of coming back. About 200 wom…
Matched conditions: EARLY BREAST CANCER
Phase: PHASE2 • Sponsor: Spanish Breast Cancer Research Group • Aim: Disease control
Last updated Jun 15, 2026 18:56 UTC
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New biosimilar aims to match leading breast cancer drug – but study halted
Disease control TerminatedThis study was designed to see if a new biosimilar drug called EG1206A works as well as the approved drug Perjeta for treating HER2-positive early breast cancer. Patients would have received the drug along with standard chemotherapy and trastuzumab before and after surgery. Howev…
Matched conditions: EARLY BREAST CANCER
Phase: PHASE3 • Sponsor: EirGenix, Inc. • Aim: Disease control
Last updated Jun 15, 2026 18:56 UTC
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Milder chemo shows promise for HER2+ breast cancer patients
Disease control OngoingThis study tests whether a less intense chemotherapy combination (paclitaxel, trastuzumab, pertuzumab) can work as well as the standard stronger regimen for people with early-stage HER2-positive breast cancer. 186 participants received either the milder or standard treatment befo…
Matched conditions: EARLY BREAST CANCER
Phase: PHASE2 • Sponsor: National Medical Research Radiological Centre of the Ministry of Health of Russia • Aim: Disease control
Last updated Jun 15, 2026 18:55 UTC
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Hope for motherhood: study tests pausing breast cancer meds for pregnancy
Disease control OngoingThis study looks at whether young women with early-stage, hormone-sensitive breast cancer can temporarily stop their hormone therapy to try to get pregnant without raising their risk of cancer coming back. It involves 518 women aged 18 to 42 who have already been on hormone thera…
Matched conditions: EARLY BREAST CANCER
Phase: NA • Sponsor: ETOP IBCSG Partners Foundation • Aim: Disease control
Last updated Jun 12, 2026 12:07 UTC
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Promising drug combo aims to stop breast cancer return in thousands
Disease control OngoingThis large phase 3 study tests whether adding the drug ribociclib to standard hormone therapy can help prevent breast cancer from returning in people with hormone receptor-positive, HER2-negative early breast cancer. Over 5,000 women and men are participating. The main goal is to…
Matched conditions: EARLY BREAST CANCER
Phase: PHASE3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 03, 2026 13:13 UTC
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Could a Chemo-Free combo beat early breast cancer?
Disease control OngoingThis study tests whether a chemotherapy-free combination of drugs (trastuzumab, pertuzumab, and T-DM1) can effectively treat HER2-positive early breast cancer. About 393 adults with early-stage disease will receive this treatment to see if it prevents cancer from returning and im…
Matched conditions: EARLY BREAST CANCER
Phase: PHASE2 • Sponsor: MedSIR • Aim: Disease control
Last updated Jun 02, 2026 11:57 UTC
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AI may predict breast cancer return better than current methods
Knowledge-focused OngoingThis study looks at whether an artificial intelligence (AI) program can accurately predict if early-stage breast cancer will come back in a different part of the body. Researchers will analyze tissue samples and health records from 2,200 women who were previously treated for ER-p…
Matched conditions: EARLY BREAST CANCER
Sponsor: Spotlight Medical • Aim: Knowledge-focused
Last updated Jun 01, 2026 17:55 UTC