EARLY BREAST CANCER
Clinical trials for EARLY BREAST CANCER explained in plain language.
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Milder chemo shows promise for HER2+ breast cancer patients
Disease control OngoingThis study tests a less intense chemotherapy combination (paclitaxel, trastuzumab, and pertuzumab) for people with early-stage HER2-positive breast cancer. The goal is to see if this gentler approach works as well as the standard stronger regimen, with fewer side effects. 186 par…
Matched conditions: EARLY BREAST CANCER
Phase: PHASE2 • Sponsor: National Medical Research Radiological Centre of the Ministry of Health of Russia • Aim: Disease control
Last updated May 01, 2026 20:42 UTC
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New hope for early breast cancer: drug combo aims to stop recurrence
Disease control OngoingThis large phase 3 trial tests whether adding the drug ribociclib to standard hormone therapy can help prevent breast cancer from returning in people with hormone receptor-positive, HER2-negative early breast cancer. About 5,100 women and men are participating. The study compares…
Matched conditions: EARLY BREAST CANCER
Phase: PHASE3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC
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New pill combo could replace chemo for some breast cancer patients
Disease control OngoingThis study tests whether a combination of two pills (letrozole and abemaciclib) works better than standard chemotherapy for women with a common type of early breast cancer (HR-positive, HER2-negative) that is at high or intermediate risk. About 200 women will receive either chemo…
Matched conditions: EARLY BREAST CANCER
Phase: PHASE2 • Sponsor: Spanish Breast Cancer Research Group • Aim: Disease control
Last updated Apr 30, 2026 15:48 UTC
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Could a Chemo-Free combo beat HER2 breast cancer?
Disease control OngoingThis study tests whether a chemotherapy-free combination of drugs (trastuzumab, pertuzumab, and T-DM1) can effectively treat HER2-positive early breast cancer. About 393 adults with early-stage disease will receive these drugs before surgery to see if the cancer disappears comple…
Matched conditions: EARLY BREAST CANCER
Phase: PHASE2 • Sponsor: MedSIR • Aim: Disease control
Last updated Apr 29, 2026 15:03 UTC
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Pausing breast cancer meds for pregnancy: safe or risky?
Knowledge-focused OngoingThis study follows 518 young women (ages 18-42) with early hormone-sensitive breast cancer who paused their hormone therapy for up to 30 months to try to get pregnant. The goal is to see if this pause increases the risk of cancer coming back. Researchers also track pregnancy rate…
Matched conditions: EARLY BREAST CANCER
Phase: NA • Sponsor: ETOP IBCSG Partners Foundation • Aim: Knowledge-focused
Last updated May 01, 2026 15:57 UTC
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AI predicts breast cancer recurrence risk in new study
Knowledge-focused OngoingThis study looks at whether an artificial intelligence (AI) program can accurately predict if early-stage breast cancer will come back. Researchers will analyze tumor samples and health records from 2,200 past patients. The goal is to see if the AI can help doctors decide which p…
Matched conditions: EARLY BREAST CANCER
Sponsor: Spotlight Medical • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:02 UTC