DUCTAL BREAST CARCINOMA IN SITU

This study tests a new radiation approach for women with early-stage breast cancer. Instead of treating the whole breast, it targets only the area where the cancer was removed, using higher daily doses over a shorter time. The goal is to see if this method causes fewer side effec…

This study compares a 1-week radiation schedule to the standard 3-week schedule for people with early-stage breast cancer who have had breast-conserving surgery. The goal is to see if the shorter treatment works just as well at controlling cancer and has fewer side effects. About…

This small pilot study tested whether a robot-assisted surgical system (da Vinci) can safely perform nipple-sparing mastectomy in 4 people with early-stage breast cancer or those needing preventive mastectomy. The goal was to see if the robot could remove all breast tissue throug…

This pilot study looks at whether adding hunger training to a standard diabetes prevention program helps obese women at high risk for breast cancer lose weight and lower their cancer risk. About 51 participants will learn weight-loss strategies and how to recognize true hunger. T…

This study tests whether the diabetes drug metformin can prevent breast cancer in women at high risk. 86 premenopausal women with atypical breast changes or genetic risk took metformin or a placebo for 12 months. Researchers checked breast tissue samples for abnormal cells to see…

This study tested whether a shorter course of higher-dose radiation (hypofractionated) works as well as standard radiation for early-stage breast cancer. About 300 women with ductal carcinoma in situ or early invasive breast cancer took part. The goal was to see if the shorter tr…

This study tests a precise type of radiation (proton beam) for women with early-stage breast cancer (stage 0 to II). The goal is to see if it keeps the breast looking good and causes fewer side effects than standard radiation. About 200 women will receive the treatment and be fol…

This study looks at how a medicated gel (afimoxifene) is absorbed through the skin of the breast in women who have had radiation for breast cancer. Researchers want to understand why absorption varies from person to person and whether radiation changes how the gel enters breast t…

This study looks at whether combining MRI scans with genetic testing can help doctors choose the best treatment for people with ductal carcinoma in situ (DCIS), a very early form of breast cancer that hasn't spread. About 368 participants will have an MRI and a genetic test on th…