DRUG INTERACTIONS
Clinical trials for DRUG INTERACTIONS explained in plain language.
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Grapefruit juice could change how depression drug works
Knowledge-focused CompletedThis study tested how grapefruit juice and the HIV drug cobicistat affect levels of esketamine, a depression treatment, in 12 healthy volunteers. Participants received esketamine as a nasal spray or oral liquid, with or without these substances. Researchers measured drug levels i…
Matched conditions: DRUG INTERACTIONS
Phase: PHASE1 • Sponsor: Helsinki University Central Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Drug combo safety check: early study completed
Knowledge-focused CompletedThis completed Phase 1 trial studied how deupirfenidone (LYT-100) and nintedanib interact in 24 healthy adults aged 18-65. Participants took both drugs over several weeks to measure drug levels and check for side effects. The goal was to understand potential drug-drug interaction…
Matched conditions: DRUG INTERACTIONS
Phase: PHASE1 • Sponsor: PureTech • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC