DIABETIC MACULAR EDEMA (DME)
Clinical trials for DIABETIC MACULAR EDEMA (DME) explained in plain language.
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New syringe could simplify High-Dose eye treatment
Disease control CompletedThis study tested a pre-filled syringe containing a high dose (8 mg) of the drug aflibercept for two eye conditions: diabetic macular edema and wet age-related macular degeneration. The main goal was to see if retina specialists could prepare and inject the drug easily and safely…
Matched conditions: DIABETIC MACULAR EDEMA (DME)
Phase: PHASE3 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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New eye drug OLN324 tested for wet AMD and diabetic swelling
Disease control CompletedThis early-phase trial tested an investigational eye injection called OLN324 in 164 adults with either wet age-related macular degeneration (AMD) or diabetic macular edema (DME). The main goal was to check safety and how the drug moves in the body, with a preliminary look at whet…
Matched conditions: DIABETIC MACULAR EDEMA (DME)
Phase: PHASE1 • Sponsor: Ollin Biosciences, Inc. • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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New antibody injection aims to tackle blinding eye diseases
Disease control CompletedThis study tested a new drug called EYE103, given as an injection into the eye, for people with diabetic macular edema (DME) or wet age-related macular degeneration (NVAMD). The trial had two parts: first, checking safety at increasing doses in about 12 people, then comparing two…
Matched conditions: DIABETIC MACULAR EDEMA (DME)
Phase: PHASE1, PHASE2 • Sponsor: EyeBiotech Ltd. • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Eye injection burden varies by disease, study finds
Knowledge-focused CompletedThis study looked at how much of a burden patients feel from repeated anti-VEGF eye injections for three different eye diseases: wet age-related macular degeneration, retinal vein occlusion, and diabetic macular edema. Researchers surveyed 393 patients about their treatment burde…
Matched conditions: DIABETIC MACULAR EDEMA (DME)
Sponsor: Hospital Hietzing • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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New eye drug brolucizumab tested in Real-World patients
Knowledge-focused CompletedThis completed study observed 572 patients with neovascular age-related macular degeneration or diabetic macular edema who were already receiving brolucizumab injections. Researchers collected routine medical data to see how well the drug resolved fluid in the eye and improved vi…
Matched conditions: DIABETIC MACULAR EDEMA (DME)
Sponsor: Novartis Pharmaceuticals • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC