DIABETIC MACULAR EDEMA (DME)

This study tests whether KHK4951 eye drops can improve vision in people with diabetic macular edema (DME), a condition where fluid builds up in the eye due to diabetes. About 150 adults with DME will use the eye drops daily for several months. The goal is to see if the drops can …

This study compares two common eye injections, aflibercept and bevacizumab, for treating diabetic macular edema (DME), a condition where fluid builds up in the center of the retina and blurs vision. About 116 adults aged 30 to 60 with diabetes for at least 5 years and reduced vis…

This early-stage study tests a new drug called EYE201, given as three eye injections over 12 weeks, for people with vision loss due to swelling in the back of the eye. The study includes patients with three different eye conditions: branch retinal vein occlusion, diabetic macular…

This study tests a new medicine called EYE103 for people with diabetic macular edema, a condition that causes vision loss due to diabetes. About 1054 adults will receive either EYE103 or a standard treatment (ranibizumab) as eye injections every 4 weeks for the first year, then l…

This early-phase study tests a single injection of avoralstat into the eye for people with diabetic macular edema, a condition that causes vision loss. Nine adults with diabetes and center-involved swelling in the retina will be monitored for safety and any signs of improvement i…

This study compares a new numbing gel (IHEEZO) to standard eye drops plus an injection for pain relief during eye injections. About 236 adults with conditions like diabetic macular edema or age-related macular degeneration will take part. The goal is to see if the gel works as we…

This study reviews existing health records from about 3000 people in Japan who received aflibercept 8 mg injections for two eye conditions that cause vision loss. Researchers will describe the patients' characteristics and how the drug was used over one year. No new treatments or…