CUTANEOUS SQUAMOUS CELL CARCINOMA
Clinical trials for CUTANEOUS SQUAMOUS CELL CARCINOMA explained in plain language.
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New drug cocktail shows promise against tough cancers
Disease control CompletedThis phase 2 trial tested a combination of two drugs, favezelimab and pembrolizumab (MK-4280A), in 163 people with either a type of skin cancer (cutaneous squamous cell carcinoma) or endometrial cancer. The goal was to see if the treatment could shrink or eliminate tumors. The st…
Matched conditions: CUTANEOUS SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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New drug combo shows promise for Tough-to-Treat head and neck cancer
Disease control CompletedThis study tested a combination of two drugs, pembrolizumab and cetuximab, in 78 people with advanced head and neck cancer that had returned or spread. The goal was to see if the combination could shrink tumors or slow the disease. Participants were grouped based on whether they …
Matched conditions: CUTANEOUS SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: University of California, San Diego • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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New shot shrinks skin cancer before surgery, early study shows promise
Disease control CompletedThis early study tested a drug called cemiplimab, which helps the immune system attack cancer cells. The drug was injected directly into skin tumors (squamous cell or basal cell carcinoma) for 3 to 12 weeks before planned surgery. The main goal was to check safety and find the ri…
Matched conditions: CUTANEOUS SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Shrinking skin cancer before surgery: new drug shows promise
Disease control CompletedThis study tested giving the drug cemiplimab before surgery to people with advanced skin cancer (stage II to IV). The goal was to see if the drug could shrink or eliminate the tumor before the operation. 79 adults took part. The main focus was on how many patients had no cancer c…
Matched conditions: CUTANEOUS SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New drug BDB001 tested in patients whose tumors resisted standard immunotherapy
Disease control CompletedThis study tested an experimental drug called BDB001 in people with advanced solid tumors (like skin, lung, or kidney cancer) that had stopped responding to standard immunotherapy. The goal was to see if BDB001 could shrink tumors or slow their growth. Only one person took part, …
Matched conditions: CUTANEOUS SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Eikon Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Real-World study shows cemiplimab effective for advanced skin cancer
Disease control CompletedThis study tracked 287 people with advanced skin cancer (squamous cell or basal cell) to see how well the drug cemiplimab works outside of a clinical trial. Researchers measured tumor shrinkage, survival, and side effects. The goal was to understand real-world effectiveness and s…
Matched conditions: CUTANEOUS SQUAMOUS CELL CARCINOMA
Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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Scientists map metabolic shifts in skin cancer development
Knowledge-focused CompletedThis study examined 119 people with precancerous or early skin cancer lesions to understand how cells change as they become cancerous. Researchers took small skin samples and analyzed their metabolism and protein markers. The goal was to learn more about the transition from harml…
Matched conditions: CUTANEOUS SQUAMOUS CELL CARCINOMA
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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New study explores what matters most to patients with high-risk head and neck skin cancer
Knowledge-focused CompletedThis study looked at how 78 patients with high-risk skin cancer on the head or neck felt about their treatment decisions, quality of life, and satisfaction with care. Researchers used standard questionnaires to measure these factors at two points: right after a team of doctors di…
Matched conditions: CUTANEOUS SQUAMOUS CELL CARCINOMA
Sponsor: Maastricht University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Could your genes affect your skin cancer risk? alabama study investigates vitamin d receptor link
Knowledge-focused CompletedThis study looked at whether certain vitamin D receptor gene variations are linked to non-melanoma skin cancer risk in an Alabama population. Researchers compared 200 people aged 50 and older, some with skin cancer and some without, by analyzing their DNA from blood samples. The …
Matched conditions: CUTANEOUS SQUAMOUS CELL CARCINOMA
Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:18 UTC