CONGENITAL ADRENAL HYPERPLASIA
Clinical trials for CONGENITAL ADRENAL HYPERPLASIA explained in plain language.
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New pill shows promise for controlling rare hormone disorder
Disease control CompletedThis study tested whether a new oral medication called SPR001 could help adults with classic congenital adrenal hyperplasia (CAH) better control their hormone levels. Twenty-four participants took increasing doses of the pill over six weeks while researchers monitored safety and …
Matched conditions: CONGENITAL ADRENAL HYPERPLASIA
Phase: PHASE2 • Sponsor: Spruce Biosciences • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Experimental drug offers new hope for controlling rare hormone disorder
Disease control CompletedThis study tested whether a new drug called CRN04894 could safely help adults with congenital adrenal hyperplasia (CAH) better control their hormone levels. Thirty-eight participants took the drug for 12 weeks while researchers checked for side effects and measured key hormones i…
Matched conditions: CONGENITAL ADRENAL HYPERPLASIA
Phase: PHASE2 • Sponsor: Crinetics Pharmaceuticals Inc. • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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Extended safety check for lifelong hormone disorder treatment
Disease control CompletedThis study followed 76 adults with congenital adrenal hyperplasia (CAH) to check the long-term safety of a medication called Chronocort. Participants either continued taking Chronocort or switched to it from their standard therapy. The main goal was to monitor for side effects an…
Matched conditions: CONGENITAL ADRENAL HYPERPLASIA
Phase: PHASE3 • Sponsor: Neurocrine UK Limited • Aim: Disease control
Last updated Mar 20, 2026 14:47 UTC
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Scientists investigate whether prenatal steroid treatment impacts Children's minds years later
Knowledge-focused CompletedThis study aimed to understand whether a steroid treatment (dexamethasone) given during pregnancy to prevent genital development issues in girls with congenital adrenal hyperplasia (CAH) affects children's thinking, memory, and emotions later in life. Researchers followed 354 chi…
Matched conditions: CONGENITAL ADRENAL HYPERPLASIA
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:18 UTC
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Scientists probe mystery of high blood pressure in rare disease
Knowledge-focused CompletedThis study aimed to understand why people with a rare genetic disorder called Cytochrome P450 Oxidoreductase (POR) deficiency often develop high blood pressure and blood vessel damage. Researchers compared 51 patients with the condition to healthy individuals, measuring blood pre…
Matched conditions: CONGENITAL ADRENAL HYPERPLASIA
Sponsor: Ozge Bayrak Demirel • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:16 UTC