CLINICALLY ISOLATED SYNDROME
Clinical trials for CLINICALLY ISOLATED SYNDROME explained in plain language.
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Lifestyle showdown: can diet and exercise replace MS drugs?
Disease control OngoingThis study looks at whether a healthy lifestyle—including diet, stress reduction, and exercise—can control symptoms and improve quality of life for people newly diagnosed with multiple sclerosis (MS) or its early stage, clinically isolated syndrome (CIS). Researchers are comparin…
Matched conditions: CLINICALLY ISOLATED SYNDROME
Phase: NA • Sponsor: Terry L. Wahls • Aim: Disease control
Last updated Jun 10, 2026 13:25 UTC
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Brain's garbage disposal may be broken in early MS, new MRI study hints
Knowledge-focused OngoingThis study looks at whether the brain's natural waste-cleaning system, called the glymphatic system, is not working properly in people with Clinically Isolated Syndrome (CIS), which is often the first sign of Multiple Sclerosis (MS). Researchers will use special MRI scans to comp…
Matched conditions: CLINICALLY ISOLATED SYNDROME
Sponsor: University of Exeter • Aim: Knowledge-focused
Last updated Jun 17, 2026 03:12 UTC
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Massive italian study tracks 96,000 MS patients to unlock better treatments
Knowledge-focused ENROLLING_BY_INVITATIONThis study is creating a large database of up to 96,000 people in Italy with multiple sclerosis (MS) and similar conditions like neuromyelitis optica. Researchers will collect information on patients' health, treatments, and test results over time. The goal is to better understan…
Matched conditions: CLINICALLY ISOLATED SYNDROME
Sponsor: Fondazione Italiana Sclerosi Multipla • Aim: Knowledge-focused
Last updated Jun 17, 2026 03:09 UTC
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AI brain scans could revolutionize MS monitoring
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at whether using an AI tool (icobrain mr) to analyze brain MRIs helps doctors spot disease activity in multiple sclerosis (MS) patients more accurately than standard scans. About 750 adults with MS or early warning signs (CIS/RIS) will be split into two groups: o…
Matched conditions: CLINICALLY ISOLATED SYNDROME
Phase: NA • Sponsor: icometrix • Aim: Knowledge-focused
Last updated Jun 09, 2026 12:07 UTC
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New MS drug shows promise in calming brain inflammation early on
Knowledge-focused OngoingThis study looks at how the drug ocrelizumab changes certain markers in the spinal fluid of people newly diagnosed with relapsing multiple sclerosis or a related early condition. Researchers want to see if starting treatment right away can reduce signs of long-term inflammation i…
Matched conditions: CLINICALLY ISOLATED SYNDROME
Phase: PHASE4 • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 08, 2026 13:16 UTC