Brain's garbage disposal may be broken in early MS, new MRI study hints

NCT ID NCT06274671

First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 31 times

Summary

This study looks at whether the brain's natural waste-cleaning system, called the glymphatic system, is not working properly in people with Clinically Isolated Syndrome (CIS), which is often the first sign of Multiple Sclerosis (MS). Researchers will use special MRI scans to compare 30 adults with CIS to healthy volunteers. The goal is to gather early evidence that this system might play a role in MS, which could lead to larger studies on disease progression.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CLINICALLY ISOLATED SYNDROME are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Royal Devon University Healthcare NHS Foundation Trust

    Exeter, United Kingdom

  • University of Exeter

    Exeter, United Kingdom

Conditions

Explore the condition pages connected to this study.