CLINICAL STAGE III GASTRIC CANCER AJCC V8
Clinical trials for CLINICAL STAGE III GASTRIC CANCER AJCC V8 explained in plain language.
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Immunotherapy combo shows promise for Hard-to-Treat stomach cancer
Disease control OngoingThis study tests whether adding chemotherapy to an immunotherapy drug (atezolizumab) works better than immunotherapy alone for patients with a specific genetic type of stomach or gastroesophageal junction cancer (MSI-H/dMMR). About 240 adults with cancer that hasn't spread far wi…
Matched conditions: CLINICAL STAGE III GASTRIC CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 17, 2026 03:31 UTC
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Shorter radiation before stomach cancer surgery shows promise in early trial
Disease control OngoingThis early-phase trial tests whether a shorter course of chemoradiation (2 weeks instead of 5) followed by standard chemotherapy is safe and effective for people with stomach cancer who will have surgery. About 25 participants will receive the shortened radiation along with chemo…
Matched conditions: CLINICAL STAGE III GASTRIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 17, 2026 03:28 UTC
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Heated chemo during surgery may stop stomach Cancer's return
Disease control ENROLLING_BY_INVITATIONThis study tests whether giving heated chemotherapy directly into the abdomen during surgery can prevent stomach cancer from returning in the belly lining. It includes 16 adults with stomach or gastroesophageal junction cancer at high risk of recurrence. The approach aims to kill…
Matched conditions: CLINICAL STAGE III GASTRIC CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 17, 2026 03:24 UTC
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New drug combo targets tough cancers in early trial
Disease control OngoingThis early-phase trial tests a new drug (BAY 1895344) combined with standard chemotherapy in people with advanced solid tumors, especially bladder cancer. The goal is to find the safest dose and see how well the combination works. About 74 adults with cancers like lung, bladder, …
Matched conditions: CLINICAL STAGE III GASTRIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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Stomach cancer combo fails to shrink tumors in early trial
Disease control OngoingThis study tested a combination of two drugs, berzosertib and irinotecan, in 17 people with advanced stomach or gastroesophageal junction cancer that had a specific genetic change (TP53 mutation) and was no longer responding to other treatments. The goal was to see if the combina…
Matched conditions: CLINICAL STAGE III GASTRIC CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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Two-Drug combo shows promise in Hard-to-Treat cancers
Disease control OngoingThis early-phase trial tests a combination of two drugs—sonidegib and pembrolizumab—in people with advanced solid tumors that have spread. The goal is to find the safest dose of sonidegib when used with pembrolizumab and to see if the pair can shrink tumors. About 36 adults with …
Matched conditions: CLINICAL STAGE III GASTRIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 08, 2026 12:00 UTC
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New combo therapy targets hard-to-treat HER2 cancers in early trial
Disease control OngoingThis early-phase trial tests a combination of two drugs—trastuzumab deruxtecan (a targeted chemotherapy) and ceralasertib (a cell-growth blocker)—in people with advanced solid tumors that have a HER2 mutation. The study first finds the safest dose, then compares the combo against…
Matched conditions: CLINICAL STAGE III GASTRIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 06, 2026 16:02 UTC
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New recovery plan may get stomach cancer patients home sooner
Symptom relief OngoingThis study looks at whether a special recovery plan helps people with stomach cancer feel better and leave the hospital sooner after surgery. About 52 patients with early to advanced stomach cancer will take part. The plan aims to reduce pain and nausea, help the bowels work soon…
Matched conditions: CLINICAL STAGE III GASTRIC CANCER AJCC V8
Sponsor: City of Hope Medical Center • Aim: Symptom relief
Last updated May 05, 2026 11:55 UTC